ID   A0A3B7A2A8_9RHOO        Unreviewed;      1122 AA.
AC   A0A3B7A2A8;
DT   16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT   16-JAN-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE            EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
DE   AltName: Full=DNA 3'-5' helicase II {ECO:0000256|ARBA:ARBA00034923};
GN   ORFNames=HYN24_02045 {ECO:0000313|EMBL:AXS78920.1};
OS   Dechloromonas sp. HYN0024.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales; Azonexaceae;
OC   Dechloromonas.
OX   NCBI_TaxID=2231055 {ECO:0000313|EMBL:AXS78920.1, ECO:0000313|Proteomes:UP000257259};
RN   [1] {ECO:0000313|EMBL:AXS78920.1, ECO:0000313|Proteomes:UP000257259}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HYN0024 {ECO:0000313|EMBL:AXS78920.1,
RC   ECO:0000313|Proteomes:UP000257259};
RA   Kim M., Yi H.;
RT   "Genome sequencing of Dechloromonas sp. HYN0024.";
RL   Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00034618};
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DR   EMBL; CP031842; AXS78920.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3B7A2A8; -.
DR   KEGG; dey:HYN24_02045; -.
DR   OrthoDB; 5905204at2; -.
DR   Proteomes; UP000257259; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.90.320.10; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR011604; PDDEXK-like_dom_sf.
DR   InterPro; IPR038726; PDDEXK_AddAB-type.
DR   InterPro; IPR011335; Restrct_endonuc-II-like.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF12705; PDDEXK_1; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13361; UvrD_C; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF52980; Restriction endonuclease-like; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR   PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000257259}.
FT   DOMAIN          7..488
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   DOMAIN          500..770
FT                   /note="UvrD-like helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51217"
FT   BINDING         28..35
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   1122 AA;  122411 MW;  27DA1F2531B1257E CRC64;
     MNSVINRLDE DSLARQRALD LASFIVEAPA GAGKTELLTQ RTLRLLAVVE HPEEVLALTF
     TNKAATEMRD RILGSLERAA RGEMPVEAHK QLTFGLAQQV LAHDAAQGWQ LLGHPGRLRI
     TTLDALCASL ARQMPYLSRF GAQPGVSEDA EAHYATAARR TLEMVESGGA DADIVAEALA
     FMDNNAGRLE KLLIAMLGRR DQWLHHASRI ESGAMKGEVE AGFSALIERD LAAVGALFNV
     RMQTLLMPLA RFAAANVADG HAPIADWHEH LRSSITDLSR WQAVAGLLLT GTGTLRKTVD
     KRIGFPADKS FADQKKAMLE LLGELRGVAG LEAVLAMLVK LPQPELSEAE WSTVECFSRL
     LRLAAGQLWL AFQEAGEVDF IEISARAGLA LGDDEAPTDL AQALDYRIRH LLVDEFQDTS
     PSQVGLIEKL TRGWMPDDGR TLFVVGDPMQ SIYRFRKADV GLFLRVRERG IGDIRLHHLR
     LFRNNRSFPA IVDWVNAAFP GIFPVADSPE AGAVRYAESA ATRPPRHDAA VVIHPVIERT
     GSDSAGDEAR CILSLIRQAR RAAPDERIAV LVRARSHLDG LVAEIRRCAP DLRFQAVDIE
     GLDGRQHVQD LLTLFRALHH RADRVHWLAL LRAPWCGLKL ADLHGLAADD RKSTIWQLMQ
     DEARLARLSA DGRQRLGHLR EVLQLAFAGR ARQHPRRWLE GVWLMLGGPR CLDAPDALKD
     VDAFFALVDK LASARQLTAE TLAAHAAELY APADPLGHAV QLMTVHKSKG LEFDTVILPG
     LHRETGGNES SLLLWDEVAG ADGEEHLLVA PIKQKGAGNG EPTAYDYLKK FEAERAAHEA
     ERLLYVAATR AIRQLHLVGV AVADDQKDDG LKPPPAGTLL DLLWPGIAQP VFVAALARDD
     GAAAEVGGID PATFVSSLVR LRQATLPDSL AVLPEGLRPA DNPLGVDEVE TSLSLEASVG
     TLVHRYLELI ARSGLEHWSM ERVAALLPVC QRWLAGQGHA AEMAASGAAE VIAALQTTIG
     SESGRWVLAR HPEAAAEQAW SNREGELAVN HVIDRVFVVD GCRWIIDYKT VRGADSELPQ
     RAASHRGQLD RYASLFAGAG LPVRRAIFFP CQGCLVELDG AK
//