ID A0A3B7MID3_9BACT Unreviewed; 593 AA.
AC A0A3B7MID3;
DT 16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT 16-JAN-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN ORFNames=D3H65_01950 {ECO:0000313|EMBL:AXY72806.1};
OS Paraflavitalea soli.
OC Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC Paraflavitalea.
OX NCBI_TaxID=2315862 {ECO:0000313|EMBL:AXY72806.1, ECO:0000313|Proteomes:UP000263900};
RN [1] {ECO:0000313|EMBL:AXY72806.1, ECO:0000313|Proteomes:UP000263900}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=5GH32-13 {ECO:0000313|EMBL:AXY72806.1,
RC ECO:0000313|Proteomes:UP000263900};
RA Weon H.-Y., Heo J., Kwon S.-W.;
RT "Genome sequencing of strain 6GH32-13.";
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
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DR EMBL; CP032157; AXY72806.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B7MID3; -.
DR KEGG; pseg:D3H65_01950; -.
DR OrthoDB; 9765670at2; -.
DR Proteomes; UP000263900; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF30; F-BOX DNA HELICASE 1; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000263900}.
FT DOMAIN 1..260
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT BINDING 21..28
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 593 AA; 67038 MW; E8CD27A559ED5A13 CRC64;
MQLTSEQKAI VGSTGDIRIN AVAGSGKTTT IMEYARARLD SRILYLAFNK AVKLEAARKF
AAPGLEHVKV ETAHSLAYKH IVFRHQYKVR AQGYKTAEVV ALLGLPGSGE RHAEHILANH
INKFVSYFCN SDKKRVQDLN YLDIVTDKAA KAFVTSFYDL IEQQTRLFLA KMDKGEIEVI
HDFYLKKFQL SGPRLPYDYI LFDEGQDASA AMLDVFFQQS ATKVIVGDTH QQIYSWRFAV
NSLEKADFKT YQLSTSFRFG QDIADLAMRV LDFKKYIDLD VPVSIKGKGT GKTVQSKAVI
ARTNLGLLLT AIDYVTEGKL KRIYFEGNIN SYTYADEGAS LYDVLNLYND KRSLIRDSLI
NSMKDMKDLE EYIEKTEDKQ LSMMVEVVKE YGSQIPAILK SIRDKHVKDE DKSKADMIFS
TVHRCKGIEY DEVQLADDFM TEERLKKTAA EKKKEDINAS KLNEEINLLY VAVTRAKRHI
FVPDAMMPEG FPFSAQVRAL LFQKEAKPPV AASVPKGKQA PGKVSRTALA KHNLSYETVR
DDYQQVYSSW TSELDDELTI MHGDEVSLSA MADHFGCTKG AVRARLKKLG LEL
//
