ID A0A3B7MJD3_9BACT Unreviewed; 2654 AA.
AC A0A3B7MJD3;
DT 16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT 16-JAN-2019, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Amino acid adenylation domain-containing protein {ECO:0000313|EMBL:AXY74564.1};
GN ORFNames=D3H65_11495 {ECO:0000313|EMBL:AXY74564.1};
OS Paraflavitalea soli.
OC Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC Paraflavitalea.
OX NCBI_TaxID=2315862 {ECO:0000313|EMBL:AXY74564.1, ECO:0000313|Proteomes:UP000263900};
RN [1] {ECO:0000313|EMBL:AXY74564.1, ECO:0000313|Proteomes:UP000263900}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=5GH32-13 {ECO:0000313|EMBL:AXY74564.1,
RC ECO:0000313|Proteomes:UP000263900};
RA Weon H.-Y., Heo J., Kwon S.-W.;
RT "Genome sequencing of strain 6GH32-13.";
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
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DR EMBL; CP032157; AXY74564.1; -; Genomic_DNA.
DR KEGG; pseg:D3H65_11495; -.
DR OrthoDB; 9778383at2; -.
DR Proteomes; UP000263900; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR CDD; cd05930; A_NRPS; 2.
DR CDD; cd19543; DCL_NRPS; 1.
DR CDD; cd19534; E_NRPS; 1.
DR CDD; cd19531; LCL_NRPS-like; 1.
DR Gene3D; 3.30.300.30; -; 2.
DR Gene3D; 3.40.50.980; -; 4.
DR Gene3D; 1.10.1200.10; ACP-like; 2.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 3.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 3.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR010060; NRPS_synth.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 2.
DR NCBIfam; TIGR01720; NRPS-para261; 1.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 2.
DR Pfam; PF13193; AMP-binding_C; 2.
DR Pfam; PF00668; Condensation; 3.
DR Pfam; PF00550; PP-binding; 2.
DR SMART; SM00823; PKS_PP; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 2.
DR SUPFAM; SSF47336; ACP-like; 2.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 6.
DR PROSITE; PS00455; AMP_BINDING; 2.
DR PROSITE; PS50075; CARRIER; 2.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 2.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000263900}.
FT DOMAIN 1043..1118
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 2558..2635
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 2654 AA; 296492 MW; 9D58FC43ED61565A CRC64;
MLELINRLAE KNISLVVAGT DLQVSFTDTG ASIPDEIIQE ISLHKAALIH YLNQYGGQRA
YLHIPAVKEA ADYAVSDGQR RLWIVSQLEE ASRAYNMPNR VVLKGSYTPA VFEAAIRKVV
DRHEILRTVF KETEGGELRQ VVIPSASFTF TVGYQELTDA SPADIDVYIS SRSATVFDLE
KGPLFLADLI RTGPEDYIFF YNVHHIISDG VSMEILGNEV LHYYHAQVQG NAGALPALAL
QYKDYAAWQQ AALRTGKLKG HQAYWLSQLE GELPVLDLPA SHQRPALLSF DGHQLSAVIN
KDLTEQLRTV CHGQQATLFM GLLGVLNTLF YRYTSQEDII IGTPVAGREH ADLENQIGFY
LNTLPLRTRF NGKHSFTELL QGIRTTTLGA YEHQAYPFDR LVTDLGLKRD NSRSVLFDVM
MVLQSQQGKS TPSMQEPGHI LTPEIVDKGA CAVKFDLQVV FTEQADGLRM DIDFNTSIYT
IEDIQRLITH YRQLLLAAVS DPVLPLYALD YLPEAEKTEL LQWGTVTKAY PVGHTLVDLF
KEQVLKRRHE IALVFENTEL TYEELDKRSD QLAAYLRLLS IPGGSPVPVC IDRSVDMIVA
LLGVLKSGCA YVPVDPAYPS DHIAYILKDT ACQVVITTAD HQGRIQDSGT GVQVVLLSDA
DHLIAVPVDG TAAVQANDLA YVIYTSGSTG RPKGVMMEHA GVVNRLRWMW EHYAFDHTDV
ILQKTSFTFD VSVWELFMPL CLGCKMVLCN KEVVSDPGSI ADLIFRHGVT CLHFVPPMLD
AFMHDLFDRA YNIRFLSSLK RVIASGEALS LASVQKWYSK MQAPLCNLYG PTEAAIDVTY
FDTDARIDKV FIGKPVANTS LYVLDDHMRL VGTGVPGELY IGGIQVARGY LNNPLLTASR
FVDDPVKKEG KLYRTGDLTR WDSSGNIEYI GRLDNQVKIR GYRIEPGEIE QVMLLSGLVK
QAVVVPQNDG SQGKCLVAYL VPQGGEGIAV IRDYLLSKLP SYMVPAYFVA MDSLPVLPNG
KINRKLLPAP AITGVPAAVS YAAPANDTER VLLEVYQLVL KRTLPGGVKD SFFESGGDSI
KAILLAGKLK QHGYKVSTRD ILKYPVLEDM AKWVQRSGQE QPAQAIIEGD STLTPIQQWL
LSKSFVNKHH FNQSVLLHSK LRIDAGIVQQ SLLELVKHHD VLRSVFVQDQ QRWKQSIKGV
ERNSVTMEVH DLVSVADPIA AMASLSEQLQ ASINLLTGPL LKAAIFRLPD GDRLLLIIHH
LVVDGVSWRI LLEDLPVLYE QLSKGDTIQL PAKTVSFQQW AKQLKLYSES EAITQELPYW
SAVAEYRTDG LRADWPEGSN LSKDSSSITV RLNETLTTSL LTEINQVYNT RVDDILLTAL
AMAVNASFEK PHLLVGLEGH GREEIIKEVD ISRTVGWFTT LYPVLLDIHS AKDIVNGLVL
VKDQLRKVPN KGIGYGIARY LLAEKPAALQ QEEQRFDVLF NYLGDLGAGV SNATGAELFS
YAKEGKGHDV DGGYEQESHM TVNAAVIQGS LQLGIRYSRE QYKRETVEGF AASYEQQLKK
LIDLLRHTPD RYLTPGDLSF KDLKMEDLIL LNAHKDVEDV YELSPLQEGI YYHWQKESDS
TAYVNQMSFR LSGQIDILLI KKSYEYLMRR HDVLRTSFHH EYENRHLQAV RKVAEPDFHY
LEVPVHADKE EFIADYKTQD RKRGFDLAKA SQMRLTVVMA PDNAYEFVWS FHHILMDGWC
SGILIKEFFI IYKSLLRGEE PRLGKVFPYV NYINWLAGQP RESTLSYWGN YLAGYDGLAE
VPFKKTLAKK STATVEEVQF TLSPEEVIAM RTLCNGLQVT ENTFIQSVWG YLLSRYNNTR
DVVFGTVVSG RPGELEGIDQ MIGLFINTVP VRLQYTGTES VKDLLQAMQQ QAIGTMPHHY
APLPDIQSQV RAGGHLFDHI VVFENFPVED IIKKGVHETQ SGEIRSLSSK VIIESNYAFT
LQVLPEASGM KISFIYDPSV LEKGSIVQIK NHFENAIRNF VARPDLPVSK IDYLSDEEYK
TLLEVYNDKV VSYPRQTILT DLKQVTAAHT AAIAVSYGAT QLSYGTLDNL SNKVAHCLAT
VYNVQPGDLV GILIDRSEWA VVLILGILKA GAAYVPIDPA YPESRIDFIA RDSRCRMIID
SGKLQDIRQA LSAYPEDTVV AREVTVHDLA YVIYTSGSTG NPKGVMINHG NLYNYLSFSQ
EKYFNRPDKR YLAPLFTSLS FDLTVTSLFG PLLCGGELVI YPQAMNVLDI LTDIFYGNRK
INFLKCTPAH IFLLHNVTGF HTAIDQLIAG GEELTATHIA LLKSINPSIE IYNEYGPTET
TVGTVVATIP AAAGAMDYPP GEAIPIGKAI TNTRLYVVDQ QVGLLPAGIK GELCIGGASV
SKGYLHNELL TARKFMEDPY WPGEQLYRTG DVVSWLPDGN MAYHGRMDDQ VKIRGYRVEP
GEIEQVLASY QDVLNTAILV HTAADGEKEL IAYLVAAEKL NMTQVREYLS HKLPAYMVPG
RFMQLDSIPL TVNGKVDKKK LPAPTDEAVP VTDEQPVQPM NDVEKRLVAI WQELLGLKGQ
EIGTRDNFFE LGGHSIKAIK ILSRISKEFG VVISIQKMFE KPTIEHLASE IMNVTWFKAE
RKADTQTTNE RIKL
//
