ID A0A3D8GME7_9BACI Unreviewed; 639 AA.
AC A0A3D8GME7;
DT 16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT 16-JAN-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN ORFNames=DRW41_16030 {ECO:0000313|EMBL:RDU35655.1};
OS Neobacillus piezotolerans.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Neobacillus.
OX NCBI_TaxID=2259171 {ECO:0000313|EMBL:RDU35655.1, ECO:0000313|Proteomes:UP000257144};
RN [1] {ECO:0000313|EMBL:RDU35655.1, ECO:0000313|Proteomes:UP000257144}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YLB-04 {ECO:0000313|EMBL:RDU35655.1,
RC ECO:0000313|Proteomes:UP000257144};
RA Yu L., Tang X.;
RT "Bacillus sp. YLB-04 draft genome sequence.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDU35655.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QNQT01000008; RDU35655.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3D8GME7; -.
DR OrthoDB; 7066673at2; -.
DR Proteomes; UP000257144; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR011528; NERD.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF13245; AAA_19; 1.
DR Pfam; PF08378; NERD; 1.
DR Pfam; PF13361; UvrD_C; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000257144}.
FT DOMAIN 14..108
FT /note="NERD"
FT /evidence="ECO:0000259|Pfam:PF08378"
FT DOMAIN 425..542
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13361"
FT DOMAIN 546..612
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13361"
SQ SEQUENCE 639 AA; 74293 MW; 73A484FBB9F7F129 CRC64;
MAITVPETIR SSATAGERLV FRTLKIYLPD DYIVYFEPEI HGRRPDFVII GPDLGLVVLE
VKDYTKNTLF RLNHEEWHIL TTSGDQAVIK SPIKQARDNV FKVVDVLKKD KSLIQTEGKY
QFNLKFPYGY GVVFTRLYAK DFVEEGLYSV IEPELCLNRD EIDPDKEGFS EEILMEKIMN
MFVVPYRLKD TLSKEDIDAI RYYLFPEVRI SAEFKPPVPY QDQLLLSLHD IKTMDLHQEN
LAKQLGDKNR LIRGVAGSGK TIILASRAKM LSKQNPDWKI LILCYNISLA NAIQQMITHM
LNEPEDLFDF NFTGGEVENP VKNHNIVVRN FHAWLKNDLK IKEGQIPNFI EKIKRKEAIL
PTYDAILIDE GQDFEADWLS LVSSLLNEQT QSLLLVEDRA QEIYKRKRTY VQDTGLSFQG
RSKILSINYR NTAQIVKFAW DFYRKHSMLK NKVVNRELEG EIIAPQSTKR KGPEPGIIRA
NNFYEEMKLV ARQMKKLHDE RKVPYHEMLV LYRVKKTSKI PIIDIIQRSI KDAGLPYFWI
TENEQSKRSF EKEDGRIKIS TIDSSKGLDF RAVFIVNTDS MPFPLEDDHE REVSLLYIGM
TRAKEFLCLS YSGTSEFTQY LDNVLLERSK QKAEKVNIK
//
