ID A0A3D8IE60_9HELI Unreviewed; 375 AA.
AC A0A3D8IE60;
DT 16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT 16-JAN-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=CCA tRNA nucleotidyltransferase {ECO:0008006|Google:ProtNLM};
GN ORFNames=CQA44_05355 {ECO:0000313|EMBL:RDU63513.1};
OS Helicobacter sp. MIT 14-3879.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=2040649 {ECO:0000313|EMBL:RDU63513.1, ECO:0000313|Proteomes:UP000256842};
RN [1] {ECO:0000313|EMBL:RDU63513.1, ECO:0000313|Proteomes:UP000256842}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MIT 14-3879 {ECO:0000313|EMBL:RDU63513.1,
RC ECO:0000313|Proteomes:UP000256842};
RA Mannion A.J., Shen Z., Fox J.G.;
RT "Novel Campyloabacter and Helicobacter Species and Strains.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the tRNA nucleotidyltransferase/poly(A)
CC polymerase family. {ECO:0000256|RuleBase:RU003953}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDU63513.1}.
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DR EMBL; NXLP01000006; RDU63513.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3D8IE60; -.
DR OrthoDB; 9805698at2; -.
DR Proteomes; UP000256842; Unassembled WGS sequence.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0031123; P:RNA 3'-end processing; IEA:UniProt.
DR CDD; cd05398; NT_ClassII-CCAase; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR Gene3D; 1.10.3090.10; cca-adding enzyme, domain 2; 1.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR002646; PolA_pol_head_dom.
DR InterPro; IPR032828; PolyA_RNA-bd.
DR PANTHER; PTHR46173; CCA TRNA NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR46173:SF1; CCA TRNA NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL; 1.
DR Pfam; PF01743; PolyA_pol; 1.
DR Pfam; PF12627; PolyA_pol_RNAbd; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR SUPFAM; SSF81891; Poly A polymerase C-terminal region-like; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP000256842};
KW RNA-binding {ECO:0000256|RuleBase:RU003953};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003953}.
FT DOMAIN 25..148
FT /note="Poly A polymerase head"
FT /evidence="ECO:0000259|Pfam:PF01743"
FT DOMAIN 176..229
FT /note="tRNA nucleotidyltransferase/poly(A) polymerase RNA
FT and SrmB- binding"
FT /evidence="ECO:0000259|Pfam:PF12627"
SQ SEQUENCE 375 AA; 44432 MW; 6EDDF10FB947A0B2 CRC64;
MKKIFNLPHQ IYQLSTLFLE HNFKIYLVGG SVRDFCLNKI PNDFDFTTSA LPNEVKYILR
DYKIFNVGEK YGTISVIFNG ILCEITTFRS ESNYLNNRHP EEIFFQKDIL VDLKRRDFSI
NAMAYDIFEH RLIDKFNGLN DLKYKIIRSI GNPNDRFEED AIRLLRAFSL ISKFSFNLSN
DTLESIIKQK KLINNLKKER ILIEINKILV GQNVLKALKL IKKYNILDIN IIPKKFQKIS
KKYRIYSSFL IFKNMELFNN KEIRLIKKIF KRLAFKRTIK ERLKLFATLR SEFELKYIFI
ALQIKISINK KNRLLKKAFS YKNLSKDLKI NGFDLQKLGY FGIDIKIIKK NLLIKMLSNN
ISNDKNSLLN EVNKT
//
