ID A0A3D8ISY3_9HELI Unreviewed; 340 AA.
AC A0A3D8ISY3;
DT 16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT 16-JAN-2019, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Formate dehydrogenase gamma subunit {ECO:0000313|EMBL:VEJ24534.1};
DE EC=1.2.1.2 {ECO:0000313|EMBL:VEJ24534.1};
DE SubName: Full=Formate dehydrogenase subunit gamma {ECO:0000313|EMBL:RDU68143.1};
GN Name=fdhC {ECO:0000313|EMBL:VEJ24534.1};
GN ORFNames=CQA62_06570 {ECO:0000313|EMBL:RDU68143.1}, NCTC13205_00677
GN {ECO:0000313|EMBL:VEJ24534.1};
OS Helicobacter cholecystus.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=45498 {ECO:0000313|EMBL:RDU68143.1, ECO:0000313|Proteomes:UP000257067};
RN [1] {ECO:0000313|EMBL:RDU68143.1, ECO:0000313|Proteomes:UP000257067}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700242 {ECO:0000313|EMBL:RDU68143.1,
RC ECO:0000313|Proteomes:UP000257067};
RA Mannion A.J., Shen Z., Fox J.G.;
RT "Novel Campyloabacter and Helicobacter Species and Strains.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:VEJ24534.1, ECO:0000313|Proteomes:UP000272814}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC13205 {ECO:0000313|EMBL:VEJ24534.1,
RC ECO:0000313|Proteomes:UP000272814};
RG Pathogen Informatics;
RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the formate dehydrogenase gamma subunit family.
CC {ECO:0000256|ARBA:ARBA00010747}.
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DR EMBL; NXLU01000012; RDU68143.1; -; Genomic_DNA.
DR EMBL; LR134518; VEJ24534.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3D8ISY3; -.
DR KEGG; hcl:NCTC13205_00677; -.
DR OrthoDB; 9790598at2; -.
DR Proteomes; UP000257067; Unassembled WGS sequence.
DR Proteomes; UP000272814; Chromosome 1.
DR GO; GO:0009326; C:formate dehydrogenase complex; IEA:InterPro.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR GO; GO:0008863; F:formate dehydrogenase (NAD+) activity; IEA:InterPro.
DR GO; GO:0022904; P:respiratory electron transport chain; IEA:InterPro.
DR Gene3D; 1.20.950.20; Transmembrane di-heme cytochromes, Chain C; 1.
DR InterPro; IPR011577; Cyt_b561_bac/Ni-Hgenase.
DR InterPro; IPR016174; Di-haem_cyt_TM.
DR InterPro; IPR006471; Formate_DH_gsu.
DR NCBIfam; TIGR01583; formate-DH-gamm; 1.
DR PANTHER; PTHR30074:SF6; BLL5475 PROTEIN; 1.
DR PANTHER; PTHR30074; FORMATE DEHYDROGENASE, NITRATE-INDUCIBLE, CYTOCHROME B556 FDN SUBUNIT; 1.
DR Pfam; PF01292; Ni_hydr_CYTB; 1.
DR SUPFAM; SSF81342; Transmembrane di-heme cytochromes; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000313|EMBL:VEJ24534.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000257067};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..340
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5033372888"
FT TRANSMEM 97..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 141..162
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 177..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 271..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 135..306
FT /note="Cytochrome b561 bacterial/Ni-hydrogenase"
FT /evidence="ECO:0000259|Pfam:PF01292"
SQ SEQUENCE 340 AA; 37546 MW; 54C841AC1CF700BB CRC64;
MKSIKYWLLF ALLSVFLHAQ APKEPVDFSH NTEIYGVKQI EQIKNWGLDS PTSGVVSGSV
IQMQGVGIGA LDNAKPLKGI EATRGLGELF TILQGKYFAP IFLAILILVP LAFAGHLIIF
KSKVFSHGVK YKIFSNYNIA IHWLAAVPFV AICITGVIMV FGDKFGGGSF VRLARDIHGI
CTIAFAIFGP LMFLMWVKAS LPKSYDLKWL LMLGGYLTPG KTISKPIPSG QFNAGMKMWF
WTCTVGGFIM IITGAFLFFQ FAPINALRLS ALIHNFLGFA IIALLFTHIY MSVFAIEGAL
SAMTDGTMGE EELAILHSYY YNELKSQGKL EKLKVQTSHH
//
