ID A0A3D8IY01_9HELI Unreviewed; 376 AA.
AC A0A3D8IY01;
DT 16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT 16-JAN-2019, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE SubName: Full=N-acetylneuraminic acid synthetase {ECO:0000313|EMBL:VEJ24684.1};
DE SubName: Full=UDP-N-acetylglucosamine 2-epimerase (Hydrolyzing) {ECO:0000313|EMBL:RDU70138.1};
GN Name=neuC {ECO:0000313|EMBL:RDU70138.1};
GN ORFNames=CQA62_01635 {ECO:0000313|EMBL:RDU70138.1}, NCTC13205_00837
GN {ECO:0000313|EMBL:VEJ24684.1};
OS Helicobacter cholecystus.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=45498 {ECO:0000313|EMBL:RDU70138.1, ECO:0000313|Proteomes:UP000257067};
RN [1] {ECO:0000313|EMBL:RDU70138.1, ECO:0000313|Proteomes:UP000257067}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700242 {ECO:0000313|EMBL:RDU70138.1,
RC ECO:0000313|Proteomes:UP000257067};
RA Mannion A.J., Shen Z., Fox J.G.;
RT "Novel Campyloabacter and Helicobacter Species and Strains.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:VEJ24684.1, ECO:0000313|Proteomes:UP000272814}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC13205 {ECO:0000313|EMBL:VEJ24684.1,
RC ECO:0000313|Proteomes:UP000272814};
RG Pathogen Informatics;
RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NXLU01000001; RDU70138.1; -; Genomic_DNA.
DR EMBL; LR134518; VEJ24684.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3D8IY01; -.
DR KEGG; hcl:NCTC13205_00837; -.
DR OrthoDB; 9803238at2; -.
DR Proteomes; UP000257067; Unassembled WGS sequence.
DR Proteomes; UP000272814; Chromosome 1.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0008761; F:UDP-N-acetylglucosamine 2-epimerase activity; IEA:InterPro.
DR GO; GO:0006047; P:UDP-N-acetylglucosamine metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR020004; UDP-GlcNAc_Epase.
DR InterPro; IPR003331; UDP_GlcNAc_Epimerase_2_dom.
DR InterPro; IPR029767; WecB-like.
DR NCBIfam; TIGR03568; NeuC_NnaA; 1.
DR PANTHER; PTHR43174; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR PANTHER; PTHR43174:SF3; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR Pfam; PF02350; Epimerase_2; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000257067}.
FT DOMAIN 23..359
FT /note="UDP-N-acetylglucosamine 2-epimerase"
FT /evidence="ECO:0000259|Pfam:PF02350"
SQ SEQUENCE 376 AA; 42838 MW; FAA8B4FE00F02207 CRC64;
MKKIVFLSGT RADWGKIKAL VQRVKESKKF DYKIFACGMH LLELYGKTFI EIYKDGFDEV
FLAKAYRHQE RMDLALSDII KQFSSFVKAY QPDMIVVHGD RIEAFAGAVV GAFNNILVAH
IEGGEVSGTI DESIRHSISK LSHLHFVANA EAKKRLMQLG EKEEDIFIIG SPDIDLMLGS
LPSIQEVQEH YYQIKPFKGE YALFLYHPVT TEEKFLHKHI TQTLKALQKS KENYIVIYPN
NDLGSKTILK AFKILQTDTH FALFKSLKFE AFLTLLKHSK FIIGNSSAGI REAPIYGIPC
INLGSRQEGR YKEGRGIVSI KESEKEILQA IKKVQGLKLP PCLEFGKGKS AQEFIKVLET
EKIWSKKLQK KFMDIL
//
