ID A0A3D8LE00_9BACT Unreviewed; 608 AA.
AC A0A3D8LE00;
DT 16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT 16-JAN-2019, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=Penicillin-binding protein 2 {ECO:0000313|EMBL:RDV15573.1};
GN Name=mrdA {ECO:0000313|EMBL:RDV15573.1};
GN ORFNames=DXT99_08790 {ECO:0000313|EMBL:RDV15573.1};
OS Pontibacter diazotrophicus.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Hymenobacteraceae;
OC Pontibacter.
OX NCBI_TaxID=1400979 {ECO:0000313|EMBL:RDV15573.1, ECO:0000313|Proteomes:UP000256708};
RN [1] {ECO:0000313|Proteomes:UP000256708}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H4X {ECO:0000313|Proteomes:UP000256708};
RA Liu Z.-W., Du Z.-J.;
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDV15573.1}.
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DR EMBL; QRGR01000008; RDV15573.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3D8LE00; -.
DR OrthoDB; 9766847at2; -.
DR Proteomes; UP000256708; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0009002; F:serine-type D-Ala-D-Ala carboxypeptidase activity; IEA:InterPro.
DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR InterPro; IPR017790; Penicillin-binding_protein_2.
DR NCBIfam; TIGR03423; pbp2_mrdA; 1.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000256708};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 9..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 51..213
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 254..578
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 608 AA; 67346 MW; 6CFCFB90A22E4B41 CRC64;
MNYLETRKYI IQGIFLLVGA LFALRLFYIQ VVDSSYKQAA ETNAIKSVIQ YPFRGLIYDR
NGELLVQNTP VYDLMVIPKE VKALDTLRLV ELVNLPLEDV RERLKKARSF SYVQPSAFYQ
KLSTEEFARI QDNLIDFPGF YINARTARGY PHQSLAHALG YIAEISPKQL DDSTYRGYRP
GDYIGKSGIE LEYEQYLMGK RGVKYKMVNV RGVEKGSFKD GAYDTLSVAG ENLISTIDLD
LQAYGEFLMN GAKGSIVAIE PSTGEILAYV SAPFYDPNLF TGKDYGKNYM TLLTDSNKTM
FNRPIMASSN PPGSIFKLAQ ALVALQEGVI TPNTGYPCNQ SLVKCSHAHA APSNLSIAIQ
TSCNPYFYQV FRALINQGKS KNTYKDTAIG LADWREQILT FGFGTELGID LPNEKKGIIA
STDMYDGVYG ENRWKFSTIY SLSIGQGELG VTPLQMANFM ATIANRGYYI NPHIIRSVGE
KGKPLPEYQK KNYTAVDAKH FTPVVDGMAA VVESGTGRNA NLSKLGIAVC GKTGTAENPQ
GKDHAVFVAF APKDNPKIAI AVYVENAGFG AQSAAPIAGL MIEQYLTDSV TRKSMEKWVL
SREYLNVK
//
