ID A0A3D8QCU8_9HELO Unreviewed; 678 AA.
AC A0A3D8QCU8;
DT 16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT 16-JAN-2019, sequence version 1.
DT 24-JAN-2024, entry version 13.
DE RecName: Full=Nucleolar complex-associated protein 3 {ECO:0000256|PIRNR:PIRNR028977};
GN ORFNames=BP6252_12763 {ECO:0000313|EMBL:RDW59676.1};
OS Coleophoma cylindrospora.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Dermateaceae; Coleophoma.
OX NCBI_TaxID=1849047 {ECO:0000313|EMBL:RDW59676.1, ECO:0000313|Proteomes:UP000256645};
RN [1] {ECO:0000313|EMBL:RDW59676.1, ECO:0000313|Proteomes:UP000256645}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BP6252 {ECO:0000313|EMBL:RDW59676.1,
RC ECO:0000313|Proteomes:UP000256645};
RX PubMed=30018880; DOI=10.5598/imafungus.2018.09.01.13;
RA Wingfield B.D., Bills G.F., Dong Y., Huang W., Nel W.J.,
RA Swalarsk-Parry B.S., Vaghefi N., Wilken P.M., An Z., de Beer Z.W.,
RA De Vos L., Chen L., Duong T.A., Gao Y., Hammerbacher A., Kikkert J.R.,
RA Li Y., Li H., Li K., Li Q., Liu X., Ma X., Naidoo K., Pethybridge S.J.,
RA Sun J., Steenkamp E.T., van der Nest M.A., van Wyk S., Wingfield M.J.,
RA Xiong C., Yue Q., Zhang X.;
RT "IMA Genome-F 9: Draft genome sequence of Annulohypoxylon stygium,
RT Aspergillus mulundensis, Berkeleyomyces basicola (syn. Thielaviopsis
RT basicola), Ceratocystis smalleyi, two Cercospora beticola strains,
RT Coleophoma cylindrospora, Fusarium fracticaudum, Phialophora cf. hyalina,
RT and Morchella septimelata.";
RL IMA Fungus 9:199-223(2018).
CC -!- FUNCTION: Required for synthesis of 60S ribosomal subunits and the
CC transport of pre-ribosomes from the nucleoplasm to the cytoplasm.
CC {ECO:0000256|PIRNR:PIRNR028977}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604, ECO:0000256|PIRNR:PIRNR028977}.
CC -!- SIMILARITY: Belongs to the CBF/MAK21 family.
CC {ECO:0000256|ARBA:ARBA00007797, ECO:0000256|PIRNR:PIRNR028977}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDW59676.1}.
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DR EMBL; PDLM01000016; RDW59676.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3D8QCU8; -.
DR STRING; 1849047.A0A3D8QCU8; -.
DR Proteomes; UP000256645; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR InterPro; IPR005612; CCAAT-binding_factor.
DR InterPro; IPR011501; Noc3_N.
DR InterPro; IPR016903; Nucleolar_cplx-assoc_3.
DR PANTHER; PTHR14428; NUCLEOLAR COMPLEX PROTEIN 3; 1.
DR PANTHER; PTHR14428:SF5; NUCLEOLAR COMPLEX PROTEIN 3 HOMOLOG; 1.
DR Pfam; PF03914; CBF; 1.
DR Pfam; PF07540; NOC3p; 1.
DR PIRSF; PIRSF028977; Nucleolar_complex_p3; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000256645};
KW Ribosome biogenesis {ECO:0000256|PIRNR:PIRNR028977}.
FT DOMAIN 122..213
FT /note="Nucleolar complex-associated protein 3 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF07540"
FT DOMAIN 475..665
FT /note="CCAAT-binding factor"
FT /evidence="ECO:0000259|Pfam:PF03914"
FT REGION 1..87
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 17..47
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 48..67
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 678 AA; 75494 MW; D03F4A1017424D1B CRC64;
MARIPAVKRR KLTPPPTDEG ESSSSTLEAV PDTNSFFKQA SSWNLEQDYE NRPRKGKKQD
KESTRLPIKT SDGQVQQVEA PEEVAEAQSD LEWLAEDGSD EEEEVEEEVK KPEVPMRQQI
LEAKEEMARI AMMLNEDPEE NGGAFKSLAQ FGQSKNTTIK KLALATQLAV YKDVIPGYRI
RPLSEQDMEV KVSKEVKKLR AYEQSLVGGY QAYIRELAKL AQSGKSGTSR DGGPSLGSIA
IACACTLLTS VPHFNFRGEL LKILVNKLAG RKVDNDFVKC RETLETLFQN DEDGTPSLDA
VSLITKMMKS KGYRVDESVL NTFLHLRLLK EFSWKASTNH VDKESMDGGK QLKQKRVFRT
KKERKLAKER KVVEKEMVQA DASVTHEERD RMQSETLKLV FVTYFRILKI RSPNLMGAVL
EGLARYAHLI NQDFFGDLLE ALKDLIGHAE SGDDVEAEEG ESEDTEDTRN LTREALLCII
TAFALLEGQD AAKAQATLSL DLSFFVTHLY RTLYALSLNP DIELSAKSLH LPDPNNPSAP
PLAAANNKIN IQTTTVLLLR SLSSVLVPAL GARAVPPLRI AAFTKQLLTS SLQLPEKSAI
AMMGLLGKVT KTHEKKVAAL WNTEERRGDG QFDPLGQEVE GSNPFATTIW EGELLKKHFS
PAVRDGVKVM EKNILGLR
//
