ID A0A3D8RL41_9EURO Unreviewed; 471 AA.
AC A0A3D8RL41;
DT 16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT 16-JAN-2019, sequence version 1.
DT 03-MAY-2023, entry version 17.
DE RecName: Full=uridine/cytidine kinase {ECO:0000256|ARBA:ARBA00012137};
DE EC=2.7.1.48 {ECO:0000256|ARBA:ARBA00012137};
GN ORFNames=DSM5745_07332 {ECO:0000313|EMBL:RDW74670.1};
OS Aspergillus mulundensis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=1810919 {ECO:0000313|EMBL:RDW74670.1, ECO:0000313|Proteomes:UP000256690};
RN [1] {ECO:0000313|EMBL:RDW74670.1, ECO:0000313|Proteomes:UP000256690}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 5745 {ECO:0000313|EMBL:RDW74670.1,
RC ECO:0000313|Proteomes:UP000256690};
RX PubMed=30018880; DOI=10.5598/imafungus.2018.09.01.13;
RA Wingfield B.D., Bills G.F., Dong Y., Huang W., Nel W.J.,
RA Swalarsk-Parry B.S., Vaghefi N., Wilken P.M., An Z., de Beer Z.W.,
RA De Vos L., Chen L., Duong T.A., Gao Y., Hammerbacher A., Kikkert J.R.,
RA Li Y., Li H., Li K., Li Q., Liu X., Ma X., Naidoo K., Pethybridge S.J.,
RA Sun J., Steenkamp E.T., van der Nest M.A., van Wyk S., Wingfield M.J.,
RA Xiong C., Yue Q., Zhang X.;
RT "IMA Genome-F 9: Draft genome sequence of Annulohypoxylon stygium,
RT Aspergillus mulundensis, Berkeleyomyces basicola (syn. Thielaviopsis
RT basicola), Ceratocystis smalleyi, two Cercospora beticola strains,
RT Coleophoma cylindrospora, Fusarium fracticaudum, Phialophora cf. hyalina,
RT and Morchella septimelata.";
RL IMA Fungus 9:199-223(2018).
CC -!- PATHWAY: Pyrimidine metabolism; UMP biosynthesis via salvage pathway;
CC UMP from uridine: step 1/1. {ECO:0000256|ARBA:ARBA00004690}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDW74670.1}.
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DR EMBL; PVWQ01000008; RDW74670.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3D8RL41; -.
DR STRING; 1810919.A0A3D8RL41; -.
DR OrthoDB; 180154at2759; -.
DR UniPathway; UPA00574; UER00637.
DR Proteomes; UP000256690; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004849; F:uridine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0044206; P:UMP salvage; IEA:UniProtKB-UniPathway.
DR CDD; cd06223; PRTases_typeI; 1.
DR CDD; cd02023; UMPK; 1.
DR Gene3D; 3.40.50.2020; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000836; PRibTrfase_dom.
DR InterPro; IPR006083; PRK/URK.
DR InterPro; IPR029057; PRTase-like.
DR InterPro; IPR000764; Uridine_kinase-like.
DR PANTHER; PTHR10285; URIDINE KINASE; 1.
DR PANTHER; PTHR10285:SF215; URIDINE KINASE; 1.
DR Pfam; PF00485; PRK; 2.
DR Pfam; PF14681; UPRTase; 1.
DR PRINTS; PR00988; URIDINKINASE.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53271; PRTase-like; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000256690};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 27..164
FT /note="Phosphoribulokinase/uridine kinase"
FT /evidence="ECO:0000259|Pfam:PF00485"
FT DOMAIN 182..232
FT /note="Phosphoribulokinase/uridine kinase"
FT /evidence="ECO:0000259|Pfam:PF00485"
SQ SEQUENCE 471 AA; 52846 MW; 509197F1F4017D7D CRC64;
MESIGPVYSA ATKSDRCYSP PWADLSIIGI AGSSGSGKTS VAMEIVKSLN LPWVVILVMD
SFYKTLNPEQ HAKAHANEFD FDSPDSIDFD VLVQCLRDLK RGKKVDIPVY SFVEHQRQAH
TTPLYSPHVL ILEGILALHD PRIMELLDVK IFVEADMDVC LGRRGEYLQF EDGQLSDRAY
PVLRDVKERG RDIDGIIKQW FNFVKPSYKK FVEPQRSVSD IIIPRGIENK TAIGMVVQHI
QRTLEEKSEK HSATLQELRR IASEEQLSPN VVMMPQTPQS TGINTILQNP DTEQVDFVFY
FDRLAALLIE KALDFTSYTP KEVETPKNTF YNGLNQEGIV SAVAILRGGS CLETALKRTI
PDCVTGRVLI RTNEANEEPQ LHYLKLPPGI EQHSTVMLLD SQMSSGGAAL MAVRVLIDHG
VAEEKIIFVT CAAVQSGVKR LGAVYPHVKV IVGRIEEESE PRWMENRYFG C
//
