ID A0A3D8RRJ2_9EURO Unreviewed; 1394 AA.
AC A0A3D8RRJ2;
DT 16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT 16-JAN-2019, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=IPT/TIG domain-containing protein {ECO:0000259|Pfam:PF01833};
GN ORFNames=DSM5745_06661 {ECO:0000313|EMBL:RDW76669.1};
OS Aspergillus mulundensis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=1810919 {ECO:0000313|EMBL:RDW76669.1, ECO:0000313|Proteomes:UP000256690};
RN [1] {ECO:0000313|EMBL:RDW76669.1, ECO:0000313|Proteomes:UP000256690}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 5745 {ECO:0000313|EMBL:RDW76669.1,
RC ECO:0000313|Proteomes:UP000256690};
RX PubMed=30018880; DOI=10.5598/imafungus.2018.09.01.13;
RA Wingfield B.D., Bills G.F., Dong Y., Huang W., Nel W.J.,
RA Swalarsk-Parry B.S., Vaghefi N., Wilken P.M., An Z., de Beer Z.W.,
RA De Vos L., Chen L., Duong T.A., Gao Y., Hammerbacher A., Kikkert J.R.,
RA Li Y., Li H., Li K., Li Q., Liu X., Ma X., Naidoo K., Pethybridge S.J.,
RA Sun J., Steenkamp E.T., van der Nest M.A., van Wyk S., Wingfield M.J.,
RA Xiong C., Yue Q., Zhang X.;
RT "IMA Genome-F 9: Draft genome sequence of Annulohypoxylon stygium,
RT Aspergillus mulundensis, Berkeleyomyces basicola (syn. Thielaviopsis
RT basicola), Ceratocystis smalleyi, two Cercospora beticola strains,
RT Coleophoma cylindrospora, Fusarium fracticaudum, Phialophora cf. hyalina,
RT and Morchella septimelata.";
RL IMA Fungus 9:199-223(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDW76669.1}.
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DR EMBL; PVWQ01000007; RDW76669.1; -; Genomic_DNA.
DR STRING; 1810919.A0A3D8RRJ2; -.
DR OrthoDB; 2901153at2759; -.
DR Proteomes; UP000256690; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00102; IPT; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR PANTHER; PTHR46680; NF-KAPPA-B INHIBITOR ALPHA; 1.
DR PANTHER; PTHR46680:SF3; NF-KAPPA-B INHIBITOR CACTUS; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF01833; TIG; 1.
DR SMART; SM00248; ANK; 2.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 2.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000256690};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1347..1367
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 808..876
FT /note="IPT/TIG"
FT /evidence="ECO:0000259|Pfam:PF01833"
FT REPEAT 999..1031
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1032..1064
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 88..130
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 194..276
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 411..434
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 556..738
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 756..781
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1293..1317
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 97..130
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 196..221
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 229..256
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 597..660
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 673..700
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 716..738
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1394 AA; 152170 MW; D9871C3E1D986A9B CRC64;
MGSTSSPTFS SLDPIVVDDD MVNPYQDTDM DFLDTARLQL SSENAGQDFD DLFSHASSSH
TVAESNPPCL SPAELSLKRS YQDEPLRHPE VFTSDSPAES PEDSSPSSSS ESPRNHLRHP
SVASSTSAVH SENTVMPFGY TSDDWVNPDY DGVKDESLFG FDASLPNLEG PYPAEADLES
SNKAMDAAFD FESAASSPSP LKSGIPQLKV QKGSSRSRLP RAPSSVKRKS ASPRISQTTV
PFIPRITKDT PSPFQPSRIP QVKPPSSPWG EKSPSSYLEE SFGGINMNGG SQSNSGFNFS
TNGLPFGFGF LPPSMQKTMN PEPTQPPVLT VHPTSLKSRV ETQIPIKLTL HPLPYGVKKL
RLPSHTISKP KFLAPPATER SADTVELYTS LFCTSALQDK DKLRKALAKA RGEPVYRSSS
SSPMASDEAV DEDKPLDGGE VKICAGCIQR ERKRAFRKKQ RKPEEDELFQ KHEDKRVIVF
NTHEIKDWAE PSKTATSHEN QALIPGAMQV ELPMRIACYC RHQNEKIGFQ VIFTLKDFKD
NVIAQAITNS IMITDDHKTH APSGPPAPGP PPALADGTEL PGVGVFPSGP AFDAGKSPAS
TKQSAASPSA TDLQGLQQRI TSQYQPSPSP FMDSANAGTS SNSQPSRSLS RQTSPNDFQG
PTSKRRKHSN SNRLPSELTM TKLENGQSST RASSNEPQFP ARGFASPGER PFVTSAAMSN
HFSNGPLTPI SDNNNPFLTS LQQQNLDNFI QQQLMSAPNS AQPSRPGTPG ASGRNSFQEQ
NLNLPMGPTP ATTMWPGITN AGNRLPTVIH KLVPAEGSVT GGTEVTLLGS GFYPGMEVVF
GDTLATTTTF WGDKCLNCLT PPALQPGQVV VVFKHEHPSF NQLQQQTQPM LPKQQQFFRY
VDDRELQMYR LALGILGHKL GNQADAFATA QQIMGSDYKG AFNLQKDFQG SSSGNQRQVP
GLESQGKLGD MDSRMLTYLE FIDLDDNPRA PRYNMRCATG QTLLHFASSL GLTRFVAGLL
ARGADPDVQD NVGNTAMHLA ALNGHAHIVH RLRLAGSSPT ARSIRGFTPA DLASTLPAHQ
AALIPARHYR SRSVGSLTSR RRHSSSASLH SLWESSSASG SFDYAVDDSE ETEDDEDELV
LTISRRSSVH HDVAIPLQTP EPAAPEGDAR PFSPPAALVA WRNQLQAQIN QFQQSVSNAF
PNLPALPPMP ALPDYQAMRR ITNLVPHRPT SSRGAKEGWW DMLTGNTSPG ATELPSYDEL
YPRTEGEEDE EATRAKKTSM LQAAAEAALD QHFETQASSS RSTAPEQKKE DIKDIRIGRN
IISREQQKHL REQQARRMKG LASDRNLYFF WIPLLLLVIF AWARSYIPGI SQGLSDAYEF
VKNRATQRVL DIGA
//
