ID A0A3D8RRN8_9EURO Unreviewed; 1232 AA.
AC A0A3D8RRN8;
DT 16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT 16-JAN-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Protein stu1 {ECO:0000313|EMBL:RDW76719.1};
GN ORFNames=DSM5745_06711 {ECO:0000313|EMBL:RDW76719.1};
OS Aspergillus mulundensis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=1810919 {ECO:0000313|EMBL:RDW76719.1, ECO:0000313|Proteomes:UP000256690};
RN [1] {ECO:0000313|EMBL:RDW76719.1, ECO:0000313|Proteomes:UP000256690}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 5745 {ECO:0000313|EMBL:RDW76719.1,
RC ECO:0000313|Proteomes:UP000256690};
RX PubMed=30018880; DOI=10.5598/imafungus.2018.09.01.13;
RA Wingfield B.D., Bills G.F., Dong Y., Huang W., Nel W.J.,
RA Swalarsk-Parry B.S., Vaghefi N., Wilken P.M., An Z., de Beer Z.W.,
RA De Vos L., Chen L., Duong T.A., Gao Y., Hammerbacher A., Kikkert J.R.,
RA Li Y., Li H., Li K., Li Q., Liu X., Ma X., Naidoo K., Pethybridge S.J.,
RA Sun J., Steenkamp E.T., van der Nest M.A., van Wyk S., Wingfield M.J.,
RA Xiong C., Yue Q., Zhang X.;
RT "IMA Genome-F 9: Draft genome sequence of Annulohypoxylon stygium,
RT Aspergillus mulundensis, Berkeleyomyces basicola (syn. Thielaviopsis
RT basicola), Ceratocystis smalleyi, two Cercospora beticola strains,
RT Coleophoma cylindrospora, Fusarium fracticaudum, Phialophora cf. hyalina,
RT and Morchella septimelata.";
RL IMA Fungus 9:199-223(2018).
CC -!- FUNCTION: Microtubule binding protein that promotes the stabilization
CC of dynamic microtubules. Required for mitotic spindle formation.
CC {ECO:0000256|ARBA:ARBA00024889}.
CC -!- SUBUNIT: Interacts with microtubules. {ECO:0000256|ARBA:ARBA00011375}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, spindle
CC {ECO:0000256|ARBA:ARBA00004186}.
CC -!- SIMILARITY: Belongs to the CLASP family.
CC {ECO:0000256|ARBA:ARBA00009549}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDW76719.1}.
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DR EMBL; PVWQ01000007; RDW76719.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3D8RRN8; -.
DR STRING; 1810919.A0A3D8RRN8; -.
DR OrthoDB; 1369289at2759; -.
DR Proteomes; UP000256690; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0000278; P:mitotic cell cycle; IEA:UniProt.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR024395; CLASP_N_dom.
DR InterPro; IPR034085; TOG.
DR PANTHER; PTHR21567; CLASP; 1.
DR PANTHER; PTHR21567:SF9; CLIP-ASSOCIATING PROTEIN; 1.
DR Pfam; PF12348; CLASP_N; 2.
DR SMART; SM01349; TOG; 2.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00022776};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Reference proteome {ECO:0000313|Proteomes:UP000256690};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 38..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 57..304
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT DOMAIN 502..745
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT REGION 302..387
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 440..495
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 755..843
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 865..890
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 938..962
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 456..470
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 874..890
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1232 AA; 136521 MW; 51C105A3156265B9 CRC64;
MYQANPQLAV TVFLILILIA LQDVWVFLFN LSFLVARYGV YFIVSFYLLA FALHLLKPIV
ARMDQKVRDI LEALKDSKLS VDAKATRLLA LKSDIKQKNV SEKAVPLIFE CLRHAIASPF
HALYSAGFST LGHFMKRMYI QGLHRLVAAY SERLLATLMD RMGDNKDRIR YQTTHALADM
WEGAGPQIES LVIGIGLQGK NPYQKLSCLN LISLTLTHAD VTVQKAENAA MHADLMAKGY
TPHIIGCVED ADPSVRQNAR QLLVQMFSGE RDDIKHELKL ALEEHKVRQS YAREILAGIG
LDPDHYDENQ SSRPFSMQPR APSRAATASR AASRAGMRAP SRAAVSRAAS RAEISRAPSR
ADTLVERSGT AVAHRDATPA DDDAPVLYHP QPVRTSPVTS DMITATDHET VFAESITATD
YHTEESVKGK LAPLLQLHGL PESDNRLGKP VTVRPTPKPV NTTKANAKKA SSVDRQVVPA
TPGRAPKQSG RDAEPLDVQP YDLGSAQDLE RLQLTMAPFF EGKETEMNFS RREEYTILIR
RITHGNAPQK WPKFYFGFVK ETLTFIFITA HSGRTTLQTA GLRTVQSLAR VNKTKLDPLI
HIILQNVLKL ASNAKGITSQ NSNMTIIAIL ENVTCNQRVL GYILSAAKEK NQSLRIYSAN
WLGIIIDGQS RHKTHSEGVT QIASCIQGGI EDSKEDIRKA YRHTFVRFSG VFPMQAKKVL
NALPPKTQQL IEKDMSQNTK DDSGALSDPF VSTTAATTAA TTPARAPAKR PVPKKPVSTL
SAAPMRPKPP RPATAAGFQK KENESPRKHQ CRIPGPGPEL STPLTRRRQK SDPLQDASPA
KSKWVAPVPA IGNADNDDRP FGTLVVPRKR PSTSEGQQAE KVEKADMAGH VTESSADAHR
VMASWGRLAH EKEFTNQNVV DVKPRKVSIS EEIIASAPWP KPEAKERLSR TPSPERDYVD
STAVSKTPLP KRNVTLWSQN ATNAHEILLK GIERIQARTM ATDGFRKLQG LIQYHPKLFD
DEEQFAVLLI GLLDELAAQA PPSKTVLSFG TVADHKTQVL YTVKCMFENF RQFFAPYYPR
TVTALLDAER SADTGGHLVK AIENFIDDVV EASKAQYGII DGVVTHLLPI VRSEAGATEH
RMLRKSLDVI TQGLASMNEQ LKELPSDQME RLGEFVRSVM TLPAVAVKRR IFALCITLRE
MVDDERFWEI VGSKNKGVDG LLFYYQTKQA AQ
//
