ID A0A3D8SBX9_9EURO Unreviewed; 2004 AA.
AC A0A3D8SBX9;
DT 16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT 16-JAN-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Protein transport protein sec16 {ECO:0000256|RuleBase:RU364101};
GN ORFNames=DSM5745_04185 {ECO:0000313|EMBL:RDW83859.1};
OS Aspergillus mulundensis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=1810919 {ECO:0000313|EMBL:RDW83859.1, ECO:0000313|Proteomes:UP000256690};
RN [1] {ECO:0000313|EMBL:RDW83859.1, ECO:0000313|Proteomes:UP000256690}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 5745 {ECO:0000313|EMBL:RDW83859.1,
RC ECO:0000313|Proteomes:UP000256690};
RX PubMed=30018880; DOI=10.5598/imafungus.2018.09.01.13;
RA Wingfield B.D., Bills G.F., Dong Y., Huang W., Nel W.J.,
RA Swalarsk-Parry B.S., Vaghefi N., Wilken P.M., An Z., de Beer Z.W.,
RA De Vos L., Chen L., Duong T.A., Gao Y., Hammerbacher A., Kikkert J.R.,
RA Li Y., Li H., Li K., Li Q., Liu X., Ma X., Naidoo K., Pethybridge S.J.,
RA Sun J., Steenkamp E.T., van der Nest M.A., van Wyk S., Wingfield M.J.,
RA Xiong C., Yue Q., Zhang X.;
RT "IMA Genome-F 9: Draft genome sequence of Annulohypoxylon stygium,
RT Aspergillus mulundensis, Berkeleyomyces basicola (syn. Thielaviopsis
RT basicola), Ceratocystis smalleyi, two Cercospora beticola strains,
RT Coleophoma cylindrospora, Fusarium fracticaudum, Phialophora cf. hyalina,
RT and Morchella septimelata.";
RL IMA Fungus 9:199-223(2018).
CC -!- FUNCTION: Involved in the initiation of assembly of the COPII coat
CC required for the formation of transport vesicles from the endoplasmic
CC reticulum (ER) and the selection of cargo molecules. Also involved in
CC autophagy. {ECO:0000256|ARBA:ARBA00024687,
CC ECO:0000256|RuleBase:RU364101}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004397}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004397}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004397}.
CC -!- SIMILARITY: Belongs to the SEC16 family.
CC {ECO:0000256|ARBA:ARBA00005927, ECO:0000256|RuleBase:RU364101}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDW83859.1}.
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DR EMBL; PVWQ01000004; RDW83859.1; -; Genomic_DNA.
DR STRING; 1810919.A0A3D8SBX9; -.
DR OrthoDB; 1361743at2759; -.
DR Proteomes; UP000256690; Unassembled WGS sequence.
DR GO; GO:0070971; C:endoplasmic reticulum exit site; IEA:UniProt.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR GO; GO:0048208; P:COPII vesicle coating; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd09233; ACE1-Sec16-like; 1.
DR Gene3D; 1.25.40.1030; -; 1.
DR InterPro; IPR024298; ACE1_Sec16_Sec31.
DR InterPro; IPR024880; Sec16.
DR InterPro; IPR024340; Sec16_CCD.
DR InterPro; IPR024468; Sec16_N.
DR PANTHER; PTHR13402; RGPR-RELATED; 1.
DR PANTHER; PTHR13402:SF6; SECRETORY 16, ISOFORM I; 1.
DR Pfam; PF12932; Sec16; 1.
DR Pfam; PF12931; Sec16_C; 1.
DR Pfam; PF12935; Sec16_N; 1.
PE 3: Inferred from homology;
KW Autophagy {ECO:0000256|RuleBase:RU364101};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824,
KW ECO:0000256|RuleBase:RU364101};
KW ER-Golgi transport {ECO:0000256|ARBA:ARBA00022892,
KW ECO:0000256|RuleBase:RU364101}; Membrane {ECO:0000256|RuleBase:RU364101};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|RuleBase:RU364101};
KW Reference proteome {ECO:0000313|Proteomes:UP000256690};
KW Transport {ECO:0000256|RuleBase:RU364101}.
FT DOMAIN 378..616
FT /note="Sec16 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12935"
FT DOMAIN 1071..1188
FT /note="Sec16 central conserved"
FT /evidence="ECO:0000259|Pfam:PF12932"
FT DOMAIN 1246..1546
FT /note="Ancestral coatomer element 1 Sec16/Sec31"
FT /evidence="ECO:0000259|Pfam:PF12931"
FT REGION 1..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 157..354
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 366..388
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 421..503
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 564..1045
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1564..2004
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 12..28
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 77..91
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 198..224
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 263..283
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 316..347
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 366..383
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 480..498
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 595..622
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 662..686
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 687..721
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 791..805
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 815..840
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 842..874
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 875..900
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 907..921
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 932..951
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 990..1008
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1025..1045
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1569..1583
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1600..1638
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1781..1808
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1848..1863
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1871..1922
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2004 AA; 211827 MW; 6ED87FDFB80DE0FE CRC64;
MENHEAFVSW NPALRSDSNA TIEDTPTPTP APETVPVDAP PTSATDDANP DTVTALDATE
PVSIGPAPME TEAPPATTSE VADTDVAQVA TESDNVEPAA PADTTEAPSI PHDVVPDVVE
PLKAEATALL EATEEPSIAQ DAAPDVAEPS IAEATAEATV EAAGPENIAN VSSIPQDTVP
DVTEPSEAEA TARLEATHPS EATETPSASQ EAVPNVTEPS SAEVATPVDT ADPAPIPQDT
APEVAVSPRV EAITPPDTTK AETVTGEEFD QTETREDFRE EAAELLSAAV NENQDQETNL
FEPKPESEPS AAPEDGYNRL QSTQQEDEPE VQTHQLEVDT SVNAVPGSSD YPAAGWVYQQ
TPADYAASGN GEISSTNHDL WGSPKSVDNG EDRFFDQLRT QTKPIYFPPE ESRFEEGVPL
LDGSAETPVE PAPVEPAAPQ PSQLDHVFEG DEDEDDGFFN SAQKPVENEP EEPFHIHRKS
TSQVLGSLGA NQDGIASPLS PTAEEFDDIL AAAASKSPEK VEEPATEEDL AAKWQAELSD
DELDAAPAEE DLAAKWQAEL DDDDLLLDDE VGDATQDSSG LANGDGVDHN LQALGSPFGT
PQSAGRPKPA QSAYTPHQPS TADLVQGVPI PGSAPPATSA PYNANYFQPQ PELPAPMTRA
ESFADRQKEG YKSPYDLPED LAPRRKPAPR PVVPPAATMP APPPRSSSIP APPPPQLTSG
VPVPPISAAT LPSTATPAAP AVPTPKNFYE ELPLAPAQPR SRPADSGRYT PNPSTASPAV
VQPPPPAQPA TNHYAQLSGD PTQPQLHQPE RLGPYATTLT PSAQSAPAVP TVNSRYSPKP
PTLQPGVKPP VSPRYSPAPP PPAAAPPPPQ RYVSQPSVLP GQTVTLPFQP RTSSPLAHHE
KVSYQPSEPP RKSSLAQPTS PVAVQPPHIE TAATVSPRSS LDASSLQQTS PPRNPYAPPS
YIEEFSRRVS HANNNPSAYT PPPEASPFVP PRRSQTQSPT QQQAGPRLSV PTVDPLKRPA
SVHAPSSPTK ASNAYAPVQP PSHNRAVSQS LEFIPPSDGQ ELDPLQRWRG APIFKFGFGG
TVLSSFPKHI PRYSAGHTTP KIKPMPGEVK TAQLKDVLAY PEPIVQHPGP LKNKSKKKDL
VSWLSSKIAA LENQGVPQHL QAYPDSQKRH EEKALLWKTV RVLVEHDGGA QSTPELQKSL
RGVLFPHLQN DVSNPTYTDP IQSFAAEPLN ASSLSDSPDT KSLGSIHNNL LLGEREKAVW
NAADNRLWGH AMIIASTLDK SVWKQVVQEF VRREVRSSSG NAESLAALYE IFAGNFEESV
DELVPPSARA GLQMVSKVDG QGASRNSLAG LESWKDTLGL VLSNRSPQDH QALLALGRLL
LSYGRIEAAH ICLIFSRAAV FGGPDDPQAN IVLLGADHVH SSPAALLDDD AILLTEAYEY
ATSVLAASPS SALPHLLAFK LVHAWSLTDK GHKSEAQQYC DAIAAALKAT TKPSGYHNQH
LFFGVDELSA RLKQTTGDGG SWISKPSMEK VSSSMWNKFS NFVAGDDSDA ASTGSAKGGE
AGFGPFAQIS GTPTVSRSPS VTDLYGQYPM PAAQPIPTAG PSRYQPNNQY APNSPDQGRG
RSSLDSQRSA SFGLSYGQRR GSQEHVPPPE SPLYGGGPFY GSPAAGYQST PPQTSYMPLA
PVDEDMAQQA YAPPSAAPQG LFGHDSPYQP PARASFDQSY GPETPAAIPT EADSYMPPMV
STGYEPPSIG APDLEVTEEP EDEKPPKKST MDDDDDEDDI AARAEALKKA EKARKDREAD
EAFRKAAEAD AQKPAQAKSS WWGWIKGGNK EDANAAAGKP IRAKLGEESS FYYDKDLKKW
VNKKDPSSAT PARATPPPPK AMGPPSRTVS GSSMPPPPAP AGPGSRPPSV ANGPPPPSGS
PAQSSLGLPS TPGLGPARSV STGAVPPAGG ASSRPGSSAG PPPRPSTSLS HASSIDDLLG
APQARKGATA RGRKKGRYVD VMAQ
//
