ID A0A3D8SIK8_9EURO Unreviewed; 664 AA.
AC A0A3D8SIK8;
DT 16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT 16-JAN-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Rho GTPase activator {ECO:0008006|Google:ProtNLM};
GN ORFNames=DSM5745_02802 {ECO:0000313|EMBL:RDW86160.1};
OS Aspergillus mulundensis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=1810919 {ECO:0000313|EMBL:RDW86160.1, ECO:0000313|Proteomes:UP000256690};
RN [1] {ECO:0000313|EMBL:RDW86160.1, ECO:0000313|Proteomes:UP000256690}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 5745 {ECO:0000313|EMBL:RDW86160.1,
RC ECO:0000313|Proteomes:UP000256690};
RX PubMed=30018880; DOI=10.5598/imafungus.2018.09.01.13;
RA Wingfield B.D., Bills G.F., Dong Y., Huang W., Nel W.J.,
RA Swalarsk-Parry B.S., Vaghefi N., Wilken P.M., An Z., de Beer Z.W.,
RA De Vos L., Chen L., Duong T.A., Gao Y., Hammerbacher A., Kikkert J.R.,
RA Li Y., Li H., Li K., Li Q., Liu X., Ma X., Naidoo K., Pethybridge S.J.,
RA Sun J., Steenkamp E.T., van der Nest M.A., van Wyk S., Wingfield M.J.,
RA Xiong C., Yue Q., Zhang X.;
RT "IMA Genome-F 9: Draft genome sequence of Annulohypoxylon stygium,
RT Aspergillus mulundensis, Berkeleyomyces basicola (syn. Thielaviopsis
RT basicola), Ceratocystis smalleyi, two Cercospora beticola strains,
RT Coleophoma cylindrospora, Fusarium fracticaudum, Phialophora cf. hyalina,
RT and Morchella septimelata.";
RL IMA Fungus 9:199-223(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDW86160.1}.
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DR EMBL; PVWQ01000003; RDW86160.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3D8SIK8; -.
DR STRING; 1810919.A0A3D8SIK8; -.
DR OrthoDB; 5482027at2759; -.
DR Proteomes; UP000256690; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd07652; F-BAR_Rgd1; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR23176:SF138; RHO GTPASE ACTIVATOR; 1.
DR PANTHER; PTHR23176; RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN; 1.
DR Pfam; PF00611; FCH; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00055; FCH; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000256690}.
FT DOMAIN 44..324
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 471..661
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 1..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 348..457
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 145..197
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 358..380
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 381..450
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 664 AA; 72185 MW; 1121CF281A6C619D CRC64;
MADATLHDGP APNTPSPGDP GVPPLSAGSG APSGPGFEIR AGPPVVSEEL KARLDKVIYS
DIGVTTLLTR LKQSVASARD FASFLKKRSI LEEEHAQGLR KVSRTLYDAA HKSENRQGTY
SYGCVEINGF HDRMADHGLQ FAASLQQMAD NLNELAGNIE RGRKQWKHEG LNAEKRVLDA
ETLAEKAKSK YDTLAEQYDR VKTGEKAGGK FGFKGTKSVA QQEEDLLRKV QSADSDYKAK
VQAAQTARQE LIATHRPQAV HNIQQLISEC DAGLILQMQK FGTFNEKLLL GQGLSISPLK
ETGDGVSATK SLREVIQQID NQKDYHDYVL SHEFSPGAVT SDQIQYHRHP TLGGPIAPPA
SSPQSTQTKR QSVVVPQPVS QPPTSAQPPQ IPVHIPSSGP LESPQSPPYP QNPDSFAPPP
FQPPYPISAG PPPESQGMNP PPPAPKEPYP ASGTGYPSNL NLPPLKPVFG LSLDELYARD
GTAVPMIVYQ CCQAVELFGL DLEGIYRLSG SANHITQLKA LFDNDSSQVD FTNPESFNHD
VNSVAGLLKQ FFRDLPDPLL TAQAYSSFVD AARIDDDIQR RDSLHAIING LPDAHYATLR
ALILHLNKVQ EHYTHNRMNA GNIAICFGPT LMGASSGGNI ADAGWQVRVI ETILENTFQI
FDDD
//
