ID A0A3D8SVQ7_9EURO Unreviewed; 702 AA.
AC A0A3D8SVQ7;
DT 16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT 16-JAN-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=DUF726-domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=DSM5745_02150 {ECO:0000313|EMBL:RDW90375.1};
OS Aspergillus mulundensis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=1810919 {ECO:0000313|EMBL:RDW90375.1, ECO:0000313|Proteomes:UP000256690};
RN [1] {ECO:0000313|EMBL:RDW90375.1, ECO:0000313|Proteomes:UP000256690}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 5745 {ECO:0000313|EMBL:RDW90375.1,
RC ECO:0000313|Proteomes:UP000256690};
RX PubMed=30018880; DOI=10.5598/imafungus.2018.09.01.13;
RA Wingfield B.D., Bills G.F., Dong Y., Huang W., Nel W.J.,
RA Swalarsk-Parry B.S., Vaghefi N., Wilken P.M., An Z., de Beer Z.W.,
RA De Vos L., Chen L., Duong T.A., Gao Y., Hammerbacher A., Kikkert J.R.,
RA Li Y., Li H., Li K., Li Q., Liu X., Ma X., Naidoo K., Pethybridge S.J.,
RA Sun J., Steenkamp E.T., van der Nest M.A., van Wyk S., Wingfield M.J.,
RA Xiong C., Yue Q., Zhang X.;
RT "IMA Genome-F 9: Draft genome sequence of Annulohypoxylon stygium,
RT Aspergillus mulundensis, Berkeleyomyces basicola (syn. Thielaviopsis
RT basicola), Ceratocystis smalleyi, two Cercospora beticola strains,
RT Coleophoma cylindrospora, Fusarium fracticaudum, Phialophora cf. hyalina,
RT and Morchella septimelata.";
RL IMA Fungus 9:199-223(2018).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TMCO4 family.
CC {ECO:0000256|ARBA:ARBA00009824}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDW90375.1}.
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DR EMBL; PVWQ01000002; RDW90375.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3D8SVQ7; -.
DR OrthoDB; 8526at2759; -.
DR Proteomes; UP000256690; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR007941; DUF726.
DR PANTHER; PTHR17920:SF3; TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4; 1.
DR PANTHER; PTHR17920; TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4; 1.
DR Pfam; PF05277; DUF726; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000256690};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 268..291
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 311..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 52..100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 134..168
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 630..702
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..25
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 71..100
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 136..168
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 630..682
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 702 AA; 77167 MW; D63104F23E161D11 CRC64;
MWKKFREFGS DPKEGSKDKA ETKNDQDLTT ILSRPQRADL TVLIAEITQR MRDSADETFK
APTAQRSAAK DLIDLNEDAA PDADTQKLEE LKDKGRQART EYVPTAEDAK AEAHLLTTFD
DWRDSVLLRV GEVVNRDSPD QNENEKPDFD LEDERPRSSY DDEEDSTWSR LSEVYPPVET
PLIRLPKPKR LLILHSLLLL MLSLEHYNAN SRVLMLLAAS SLGLGIKTLN QDEVKVSRGL
LDAALQLPAN SDAQAQKRES DPSRKWKVGI ASVAGAVLIG VTGGLAAPFI AAGLGTVMGG
LGLGATAAAG YLGAVAGSGV IVGGLFGAYG GRMTGRMMDK YAREVDDFAF LPIHDSGRGR
KRFDDEKEAA REDHRLRVTV GITGWLTEED NFVVPWRVIG KDSEVFGLRW ETRPLMDLGH
AIDRLVTTAA WSAGRHVLTK TIFAGLISAL TLPVGLLKVA GIADNPFSVA KSRADKAGEV
LADALISKVQ GERPVTLIGY SLGSRVIFSC LQTLAKRHAY GLIESAIFLG APTPSDAPDW
RRMRRVVSGR LVNVHSENDS VLAFLYRTSS LQLGVAGLQA IENVPGVENL DVSDYINGHL
RYQYLLGRIL RTVGLECISA REVAREEAAL EARDRKEEQE RIQNERRAGI EGDSEVARRK
LESGDIAPDE ELSPRPRSEA HQSIPRRPVP VRSTEDKGKY EV
//
