ID   A0A3D8T324_9EURO        Unreviewed;       971 AA.
AC   A0A3D8T324;
DT   16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT   16-JAN-2019, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Putative Pyridoxal-dependent decarboxylase conserved protein {ECO:0000313|EMBL:RDW92952.1};
GN   ORFNames=DSM5745_00274 {ECO:0000313|EMBL:RDW92952.1};
OS   Aspergillus mulundensis.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=1810919 {ECO:0000313|EMBL:RDW92952.1, ECO:0000313|Proteomes:UP000256690};
RN   [1] {ECO:0000313|EMBL:RDW92952.1, ECO:0000313|Proteomes:UP000256690}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 5745 {ECO:0000313|EMBL:RDW92952.1,
RC   ECO:0000313|Proteomes:UP000256690};
RX   PubMed=30018880; DOI=10.5598/imafungus.2018.09.01.13;
RA   Wingfield B.D., Bills G.F., Dong Y., Huang W., Nel W.J.,
RA   Swalarsk-Parry B.S., Vaghefi N., Wilken P.M., An Z., de Beer Z.W.,
RA   De Vos L., Chen L., Duong T.A., Gao Y., Hammerbacher A., Kikkert J.R.,
RA   Li Y., Li H., Li K., Li Q., Liu X., Ma X., Naidoo K., Pethybridge S.J.,
RA   Sun J., Steenkamp E.T., van der Nest M.A., van Wyk S., Wingfield M.J.,
RA   Xiong C., Yue Q., Zhang X.;
RT   "IMA Genome-F 9: Draft genome sequence of Annulohypoxylon stygium,
RT   Aspergillus mulundensis, Berkeleyomyces basicola (syn. Thielaviopsis
RT   basicola), Ceratocystis smalleyi, two Cercospora beticola strains,
RT   Coleophoma cylindrospora, Fusarium fracticaudum, Phialophora cf. hyalina,
RT   and Morchella septimelata.";
RL   IMA Fungus 9:199-223(2018).
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RDW92952.1}.
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DR   EMBL; PVWQ01000001; RDW92952.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3D8T324; -.
DR   STRING; 1810919.A0A3D8T324; -.
DR   OrthoDB; 1607139at2759; -.
DR   Proteomes; UP000256690; Unassembled WGS sequence.
DR   GO; GO:0016830; F:carbon-carbon lyase activity; IEA:InterPro.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR002129; PyrdxlP-dep_de-COase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR049373; TyrDC_C.
DR   PANTHER; PTHR42735; -; 1.
DR   PANTHER; PTHR42735:SF4; TYROSINE DECARBOXYLASE; 1.
DR   Pfam; PF00282; Pyridoxal_deC; 2.
DR   Pfam; PF21391; tyr_de_CO2_C; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   4: Predicted;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239};
KW   Reference proteome {ECO:0000313|Proteomes:UP000256690}.
FT   DOMAIN          567..680
FT                   /note="L-tyrosine decarboxylase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF21391"
SQ   SEQUENCE   971 AA;  108377 MW;  B950E2AB18A22107 CRC64;
     MAARGDVTHQ AISSYFIGPE AENLDEFKTN IATILNELEK ARKAYFPQPP DKKFIPPEVK
     ASAEFQRLTA KFRTVIGRAA KLLGEKSVPF WSPRYQAHMC TDLSMVSLLG YFMTMLYNPN
     NVAIEASPFS TAAEILVGEQ LCDLLGYNNQ KGVADQPTGW GHVTSGGSVA NLESIWVARN
     LKFYPLSLHQ AVKRGQLQFA RKDFLVKTCA GAEKNFADLT TWELLNLRPE TVLDLPKLLH
     DQYGVSPAYI ADAIDKYNIQ TVGKTKLEQA YQITKPSRYL LTNTKHYSWP KGGAITGIGS
     ENMIGVSVDA EARVDLVDLV SKLEQCLRNE QAVYAVVAVI GSTEEGAVDR LSEILRIRKR
     FQRRGLSFLV HADAAWGGYF TSMLPRNLKK QEDLFKAAGS TSDEGFVPDL GLKVETQEDL
     LAMRFADSIT IDPHKAGYIP YPAGALVYRD ERMRSLITWA CPKPGAAAMA TWLANECIGL
     DQNGYGALLS EATFTCTRLA AHWAAMTTRE DSFICVALNR LPSEVNGGDV EGEKRFIREQ
     ILPKTNQEIV ANDAKLHTMN LLRALGSDLN INAFALNWRY EDGRLNDDIE EANYLMLRVV
     KELSISSPND EPKEKDFFLT STEFKHDEYG TCAELFMDRL GITRSKQNLM VLRNVVMSAF
     PTEHELIDDL IKRFRAVVED AVQVCRDRNA IKPDIHRFYI QGTGDIFFVY RPRFQEARFR
     RQLILKGKFS PAGFDAYIKA KAKGVVSLNT CNKTILETLL NKVANHGQAT FQGDLVDGDG
     NTISRVKTTI TKVIKNRSLS SRNREPAYPA TYMPFYLYGS STQHHISHIL LKSPNIELGA
     ANVQLSLDYP LAGDELARGA ILALTNTPEA PMQPFPTECS ERPSDFFFRA GQKFHVKIWR
     DLKRAEESGP NLLPASLEEF GPEIACGEML VRGDVLVDAS SVNGDLFDRA EDEGEQWRGL
     FRSLEGVTGG E
//