ID   A0A3D8TVK5_9LIST        Unreviewed;       721 AA.
AC   A0A3D8TVK5;
DT   16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT   16-JAN-2019, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   RecName: Full=Metallo-beta-lactamase domain-containing protein {ECO:0000259|SMART:SM00849};
GN   ORFNames=UR08_04740 {ECO:0000313|EMBL:RDX03051.1};
OS   Listeria kieliensis.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Listeriaceae; Listeria.
OX   NCBI_TaxID=1621700 {ECO:0000313|EMBL:RDX03051.1, ECO:0000313|Proteomes:UP000257055};
RN   [1] {ECO:0000313|Proteomes:UP000257055}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Kiel-L1 {ECO:0000313|Proteomes:UP000257055};
RA   Schardt J., Mueller-Herbst S., Scherer S., Huptas C.;
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RDX03051.1}.
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DR   EMBL; LARY01000001; RDX03051.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3D8TVK5; -.
DR   Proteomes; UP000257055; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR   CDD; cd07731; ComA-like_MBL-fold; 1.
DR   Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR   InterPro; IPR035681; ComA-like_MBL.
DR   InterPro; IPR004477; ComEC_N.
DR   InterPro; IPR004797; Competence_ComEC/Rec2.
DR   InterPro; IPR025405; DUF4131.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   NCBIfam; TIGR00360; ComEC_N-term; 1.
DR   NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR   PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR   PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR   Pfam; PF03772; Competence; 1.
DR   Pfam; PF13567; DUF4131; 1.
DR   Pfam; PF00753; Lactamase_B; 1.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000257055};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        16..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        196..218
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        238..261
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        268..289
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        295..312
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        319..341
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        347..373
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        416..433
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        440..459
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          470..677
FT                   /note="Metallo-beta-lactamase"
FT                   /evidence="ECO:0000259|SMART:SM00849"
SQ   SEQUENCE   721 AA;  81905 MW;  5813E1F5888404FF CRC64;
     MLFCGYLLSR KQIKKALFFF SILLFAAFYY FLTDTLNVSG QEQTAKSATV RIIQSLQIDG
     DRFSAVVNLN HEKSVLHYQI KSEKEKEQLK KIRYGAIFQV SGQIEKPNVA RNFNQFDYAD
     YLKRQKIHTI FQAEKLIPVG TKQTFTSSIQ NFRLNLLEYI HEHFSKRTAP YVAALITGDK
     STFDQDLYAE YQKLGVVHLL AISGLHVNLF VGLCYFLLLR FGFTKETSQT LLFVILPFYA
     LIAGFGAPVI RACGMTLFIL TGVKLKRLIS PICAISLVFL LSFLVNPYVV FNAGFQLSYA
     VSFAILLGRQ LIERATSSFG KALTISIIST LASALILLFH FFEFSLIGIF LNILYVPFFS
     SFLVPFIFIC FLFSKIPILL TPLNVLLDFF VTIMEHVTEL FQIFNGTMFT AGKPTGLFTL
     LLVFITFLIF LCWEKRYFKI VFFFTMLFFL SAKLSTFPFS GEVSMIDIGQ GDSILIQLPR
     NKGNYLIDTG GQIAFPKENW QKRKHSFSIG QDLLTPVLKS KGIAKLDKVF ITHAHADHMG
     ALKELASEIK IKRIYFAKNA AKKKILQEAL LKLQDIPVTE LEKGDRIGDK DYLFQVLSPY
     REVPNTNNNS LVLKVELGGL VWLFTGDAEK EIEQELLQTE DIQADILKVG HHGSKTSSTR
     AFIEKVNPDF ALISCGVKNQ FGHPNAETLV TLQKKNVQIF RTDQNGMIVY RFLKGFKTKL
     Q
//