ID A0A3D8VAB4_9GAMM Unreviewed; 416 AA.
AC A0A3D8VAB4;
DT 16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT 16-JAN-2019, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Heme biosynthesis protein HemY {ECO:0000313|EMBL:RDY66380.1};
GN ORFNames=DX912_14010 {ECO:0000313|EMBL:RDY66380.1};
OS Lysobacter soli.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Lysobacter.
OX NCBI_TaxID=453783 {ECO:0000313|EMBL:RDY66380.1, ECO:0000313|Proteomes:UP000256829};
RN [1] {ECO:0000313|EMBL:RDY66380.1, ECO:0000313|Proteomes:UP000256829}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KCTC 22011 {ECO:0000313|EMBL:RDY66380.1,
RC ECO:0000313|Proteomes:UP000256829};
RA Zhang X., Feng G., Zhu H.;
RT "Lysobacter soli KCTC 22011, whole genome shotgun sequence.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in a late step of protoheme IX synthesis.
CC {ECO:0000256|ARBA:ARBA00002962}.
CC -!- PATHWAY: Porphyrin-containing compound metabolism; protoheme
CC biosynthesis. {ECO:0000256|ARBA:ARBA00004744}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDY66380.1}.
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DR EMBL; QTJR01000010; RDY66380.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3D8VAB4; -.
DR UniPathway; UPA00252; -.
DR Proteomes; UP000256829; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0042168; P:heme metabolic process; IEA:InterPro.
DR GO; GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR005254; Heme_biosyn_assoc_TPR_pro.
DR InterPro; IPR010817; HemY_N.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR NCBIfam; TIGR00540; TPR_hemY_coli; 1.
DR Pfam; PF07219; HemY_N; 1.
DR Pfam; PF13428; TPR_14; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
PE 4: Predicted;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Porphyrin biosynthesis {ECO:0000256|ARBA:ARBA00023244};
KW Reference proteome {ECO:0000313|Proteomes:UP000256829};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 46..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 29..128
FT /note="HemY N-terminal"
FT /evidence="ECO:0000259|Pfam:PF07219"
SQ SEQUENCE 416 AA; 45122 MW; 7FE778D69AAF75EE CRC64;
MNLFRNVLFW IVLALVGALV AQLLVLDPGY VLVRYGGNDY TTNVPKAIAL LVVALAVLWL
LWKLATLPFV AMRRHRRKQS RARLIDGVDA VHRGEWTRAE KLLEQAAQEP DALAVGRIGA
ARAAMARGDE TAARAHLTAI GTANPASRAI AEAEFALAQG RASEALSILD APSATPLPPR
GLVLRGEALA SLGRSGEAYG TLGALRQQQA LSNERLGALE AQWAAASLRE AADANVLADR
WEALPKPLRN DPAAVAAYAE RAAAMRWDEA ASKSIEQALD AQWDESLAAL YGRLPVNRFE
QRRATAERWL PAHPASPALL LTLARLSRAQ GQWPQAEQYL HRALAQGGNS EAWEELGDGF
AASGEEKLAR HCYANALRAA RGEATQPLPG RDMRQTIFDQ AVVEERDAHG VPRLRE
//
