ID A0A3D9FH37_9SPHN Unreviewed; 460 AA.
AC A0A3D9FH37;
DT 16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT 16-JAN-2019, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Radical SAM protein with 4Fe4S-binding SPASM domain {ECO:0000313|EMBL:RED16968.1};
GN ORFNames=DFR46_2002 {ECO:0000313|EMBL:RED16968.1};
OS Parasphingopyxis lamellibrachiae.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Parasphingopyxis.
OX NCBI_TaxID=680125 {ECO:0000313|EMBL:RED16968.1, ECO:0000313|Proteomes:UP000256310};
RN [1] {ECO:0000313|EMBL:RED16968.1, ECO:0000313|Proteomes:UP000256310}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 26725 {ECO:0000313|EMBL:RED16968.1,
RC ECO:0000313|Proteomes:UP000256310};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RED16968.1}.
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DR EMBL; QRDP01000004; RED16968.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3D9FH37; -.
DR Proteomes; UP000256310; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR023885; 4Fe4S-binding_SPASM_dom.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR000385; MoaA_NifB_PqqE_Fe-S-bd_CS.
DR InterPro; IPR007197; rSAM.
DR NCBIfam; TIGR04085; rSAM_more_4Fe4S; 1.
DR PANTHER; PTHR11228:SF7; PQQA PEPTIDE CYCLASE; 1.
DR PANTHER; PTHR11228; RADICAL SAM DOMAIN PROTEIN; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR Pfam; PF13186; SPASM; 1.
DR SFLD; SFLDG01386; main_SPASM_domain-containing; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS01305; MOAA_NIFB_PQQE; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000256310};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 122..339
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 460 AA; 50714 MW; AF125F28840726E2 CRC64;
MGIEQNDFIP ALKSDVRLKP MNGYALAHGY HPSLIRMIDP SHAFFLALCN GTFRPAEIAY
LYGETFGLDA DDADYQASRL LDQHRMFLDF GGEPGEAVRF SPQDFLFPGD KGKIDGAAYG
KWPVPAGINV TLTFKCNFNC SYCYQDLLQT GDNRWDLGKC RELVEEAADW GVVFLGLTGG
EPTIFKGWLE LIEAGLKRGM IPTMTSNGTV IGSDPEIAQR LAAAGMEEIT ISFDAPSAEL
HDEITRSKGQ FPKVLNAVRY LVDAGLRVVI KSVLTPRTQH SVEPMIDMLV TMGVHEIGIS
FMEGGAIESG ANAADNVSMD ELRIVRDRVQ AKRELYAGTC DIHPPKDAEK VWKDGDWYPC
GGINMGMSIF PTGDVSVCDK MHGVKDFTYG NVFDRGLEAI WNGEAFADLR ERTVQPDLID
PDCAKCSKLY QCRTSCFVDA YNATGKYLAK DPHCGGPFFD
//
