ID A0A3D9HXA5_9PROT Unreviewed; 671 AA.
AC A0A3D9HXA5;
DT 16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT 16-JAN-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Xaa-Pro aminopeptidase {ECO:0000313|EMBL:RED54127.1};
GN ORFNames=DFP90_101930 {ECO:0000313|EMBL:RED54127.1};
OS Aestuariispira insulae.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Kiloniellaceae; Aestuariispira.
OX NCBI_TaxID=1461337 {ECO:0000313|EMBL:RED54127.1, ECO:0000313|Proteomes:UP000256845};
RN [1] {ECO:0000313|EMBL:RED54127.1, ECO:0000313|Proteomes:UP000256845}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT 8488 {ECO:0000313|EMBL:RED54127.1,
RC ECO:0000313|Proteomes:UP000256845};
RA Whitman W.;
RT "Genomic Encyclopedia of Type Strains, Phase III (KMG-III): the genomes of
RT soil and plant-associated and newly described type strains.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M24B family.
CC {ECO:0000256|ARBA:ARBA00008766, ECO:0000256|RuleBase:RU000590}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RED54127.1}.
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DR EMBL; QRDW01000001; RED54127.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3D9HXA5; -.
DR Proteomes; UP000256845; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR CDD; cd01085; APP; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 2.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR InterPro; IPR033740; Pept_M24B.
DR InterPro; IPR032416; Peptidase_M24_C.
DR InterPro; IPR001131; Peptidase_M24B_aminopep-P_CS.
DR PANTHER; PTHR43763; XAA-PRO AMINOPEPTIDASE 1; 1.
DR PANTHER; PTHR43763:SF6; XAA-PRO AMINOPEPTIDASE 1; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF16189; Creatinase_N_2; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR Pfam; PF16188; Peptidase_M24_C; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
DR PROSITE; PS00491; PROLINE_PEPTIDASE; 1.
PE 3: Inferred from homology;
KW Aminopeptidase {ECO:0000313|EMBL:RED54127.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU000590}; Protease {ECO:0000313|EMBL:RED54127.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000256845}.
FT DOMAIN 82..203
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 386..601
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
FT DOMAIN 612..671
FT /note="Peptidase M24 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16188"
SQ SEQUENCE 671 AA; 73269 MW; 7A683C2936AC239C CRC64;
MTYQGDSRLN QLLLENSAAM DAGEVRNLIR GVLAAPNFGD GWFDLIAPAA NDALKTELSA
LRSEIERECD AGFTDGPAPR TRIDALRAYM KEKGLAAFIV PRTDRYQGEY VPARFDRLLW
LTGYSGSAGL AVIGQEKAAM FVDGRYTLQV RQQTEEALFE YRHLITEPAW DWIAETFKAG
DRIAYDPWLH SAHGLKRLQA AVQKIGAILE PLDENPIDLI WQGQPEEPVS PVRPHALDKA
GESAVSKRER LGALLSEKQI DSAVITATDS IAWLLNIRGR DVPNCPLPLS AAILHADGAV
ELFIDDRKLT QEARESFGNA VSVQAPGTFG TRLEALGLEG RTVLADPAGS PSYVFDRLNE
SGAKLVEGED PCLLPRACKN DVELAGMRAA HKRDGAAIVK FLAWFDAHKG DEGLSELDVI
EQLAAFRNED PTCTDASFDT IAGSGPNGAV IHYRATEKTN RRLDKDSLLL VDSGAQYPDG
TTDITRTMPT HGTPSEEMKE RFTLVLKGHI QLAMARFPEG IPGQRLDTLA RAPLWSLGLD
YDHGTGHGVG SYLNVHEGPQ RIASAGNPVP LRPGMILSNE PGYYKDGDYG IRIENLVIVT
ELDGGLPEGK KVFGFETITL APIEPSLIKV DLLSEAERDW LNAYHAKVLK EIGPLVDGDE
LAWLEKATAA I
//
