ID A0A3D9IUW4_9BACL Unreviewed; 605 AA.
AC A0A3D9IUW4;
DT 16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT 16-JAN-2019, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=DFP98_12058 {ECO:0000313|EMBL:RED65309.1};
OS Cohnella phaseoli.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Cohnella.
OX NCBI_TaxID=456490 {ECO:0000313|EMBL:RED65309.1, ECO:0000313|Proteomes:UP000256977};
RN [1] {ECO:0000313|EMBL:RED65309.1, ECO:0000313|Proteomes:UP000256977}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT 7287 {ECO:0000313|EMBL:RED65309.1,
RC ECO:0000313|Proteomes:UP000256977};
RA Whitman W.;
RT "Genomic Encyclopedia of Type Strains, Phase III (KMG-III): the genomes of
RT soil and plant-associated and newly described type strains.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RED65309.1}.
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DR EMBL; QRDZ01000020; RED65309.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3D9IUW4; -.
DR OrthoDB; 9776552at2; -.
DR Proteomes; UP000256977; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR Gene3D; 1.10.8.500; HAMP domain in histidine kinase; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF06580; His_kinase; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:RED65309.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 22..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 316..337
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 335..388
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 431..602
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 605 AA; 68634 MW; 2118F826468773C6 CRC64;
MRNAVIKGIV GAVNNIGLRK KLYTSLLVFI FIPLLVFGYY LYDKFSARLI DQFEYTAGQA
FEQTAGYLEY KIFNVNSIAN IVMMESKIQE LFKYTPSDKY NESIIQDEYY RDNLNFLYSL
ERSKDIYRIG LYVPSELVFA NERDHFFNWS SLAESGIVER MEENGGKLIW LPSGILDPGH
GGQTNLISAL CRIRNLGNYH QTLGACRIDL LESDVHDIIA RARATPSSLV ALVNENGQTI
TSVGDPQLLA AGLEQQEISD ILQEPGEAQV SAKIKIENRH GVLLYKDVKG TDWKLLSFIP
DEDMLRTTES VKKETAVFVL VLCVLAYGFA IFISSTITSR IKKLVVQLKQ TERGDFKQPV
VFRGGHDEIG QLGMKFNHML GKISDLIEEK YNLGKSVKGA ELKALQAQIN PHFLYNTLEC
IRWMTKENKS EEINRLLYLL AKFYRLSLSK GEEVISLRDE LEHIKAYVEI QNIRFDDSIQ
LEIDVPEELL ELNLIKLVLQ PIVENSILHG ILEKENGTGR IQVKAECQGE ELELSVTDDG
PGIEEEVLKN ILNSDKRSRN SGYGIKNVNE RIKLYYGSEY GLEYRSVYGE GTTVRIRLPA
HGAVL
//
