ID A0A3D9KG38_9BACL Unreviewed; 593 AA.
AC A0A3D9KG38;
DT 16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT 16-JAN-2019, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=DFP98_104176 {ECO:0000313|EMBL:RED85471.1};
OS Cohnella phaseoli.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Cohnella.
OX NCBI_TaxID=456490 {ECO:0000313|EMBL:RED85471.1, ECO:0000313|Proteomes:UP000256977};
RN [1] {ECO:0000313|EMBL:RED85471.1, ECO:0000313|Proteomes:UP000256977}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT 7287 {ECO:0000313|EMBL:RED85471.1,
RC ECO:0000313|Proteomes:UP000256977};
RA Whitman W.;
RT "Genomic Encyclopedia of Type Strains, Phase III (KMG-III): the genomes of
RT soil and plant-associated and newly described type strains.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RED85471.1}.
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DR EMBL; QRDZ01000004; RED85471.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3D9KG38; -.
DR OrthoDB; 9776552at2; -.
DR Proteomes; UP000256977; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd18774; PDC2_HK_sensor; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF06580; His_kinase; 1.
DR SMART; SM00304; HAMP; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:RED85471.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 14..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 299..317
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 319..371
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 409..588
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 593 AA; 66717 MW; 9A53B8E85F25171E CRC64;
MMRLFDFLKL HQKWLLAIFS LIVVPLVVYT YLSYAKMADM AKKQTIQLAE KTTGRTASEL
GFLTASSINA LDILSLDRNM NEMLSQNPDE HPIPLQLRDY ANIVNFANTL ERNKDFYRVR
LYVRDDFVYA NDHVNLFGLS QALSEQWGED LTRSGQNAHW FIPQEDENAD GTPPLVSVAR
KMLNLDNFTR TNGVIRIDIL QSTLTDKLTD TKITDGALVY LQNVQGQIIA RSDPELGPEG
LPAAKEWLSL PANEWNTRRI GNTSVMLSHR AVEGSDWSLV TVVPVKEVLA GITALRNQLI
AILLSIVLFA YFLAYLASKA GTKKIKHLIK RMKKVQSGDL NVIISRYGKD ELGELVENFN
YMIVKLTGLM NEHVQLGIAL RSADLRTLQS QINPHFLYNS LDLINCTAIE HQVPDITKMV
RALTKYYKIG LSKGMNIVSL ESELEHAKAY VQIMNMRYAD AVEFNIDIDT SLLCCRIPKI
TLQPLVENAI LHGILEKENK RGTIRLTGRR DHAAIRLFLE DDGIGIPANK LGTLFSHNAH
DLQQAESGIG IQNTHDRLRL AYGEAFGLNL KSEPGRGTIV EIRFPGDSGF EDK
//
