ID A0A3D9LHK0_9MICC Unreviewed; 555 AA.
AC A0A3D9LHK0;
DT 16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT 16-JAN-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=C8E99_3026 {ECO:0000313|EMBL:REE05156.1};
OS Citricoccus muralis.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Citricoccus.
OX NCBI_TaxID=169134 {ECO:0000313|EMBL:REE05156.1, ECO:0000313|Proteomes:UP000256727};
RN [1] {ECO:0000313|EMBL:REE05156.1, ECO:0000313|Proteomes:UP000256727}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14442 {ECO:0000313|EMBL:REE05156.1,
RC ECO:0000313|Proteomes:UP000256727};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:REE05156.1}.
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DR EMBL; QREH01000001; REE05156.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3D9LHK0; -.
DR Proteomes; UP000256727; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR45436:SF5; SENSOR HISTIDINE KINASE TRCS; 1.
DR PANTHER; PTHR45436; SENSOR HISTIDINE KINASE YKOH; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:REE05156.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000256727};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 30..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 180..202
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 204..257
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 272..507
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT REGION 487..555
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 555 AA; 59667 MW; B485BB9B300D22C9 CRC64;
MPATVNRAGR FRPFHELARL WKTSSLRTQL VVMTTGLMLL AVIVTAALTA SLFRQELVRQ
IDDDLHANRN NVSVYLTSLG TDTGYFSSPQ SILRFYGELQ DNHGNTTTNS SFTGANEDRP
VVPSLTADEV LERGNEAFDV SGTTEASRGW RVTMYRLASG EGSLAIALPL EPVHDSVDRV
TSLVVTIGLL ATAGASVIAY AVTTRAFKPL LRVERTAAQI AAGDLSRRVE MGAPDTEVGR
LSRSLNAMLA HIETAFRSKE QSEERMRRFI QDASHELRTP LVTIRGFSEL YRHGGISDPD
DVGAAMGRIE GEAKRMGQLV EDLLTLARLD EQRPLEHRPV DLMLLAHDAV LDARVNAPDR
EISLEGLDGG RAGSAPTLGD EGKIRQVVTN LVTNALRYSP AGTPLEIAVG TVDVLPGSVH
ADGRQVHGSR DCVIEIRDHG PGIDEQDASR VFERFYRADS SRQRETGGTG LGLAIVAAIV
AQHDGTVRLD QTPGGGATMS VRMPWVDPSA DEDDQTPDEA GTEVQGGQED TSAGPPVIPP
RPPQAPGSGH SSTSG
//
