ID   A0A3D9Q3P2_9BACL        Unreviewed;       745 AA.
AC   A0A3D9Q3P2;
DT   16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT   16-JAN-2019, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=RND superfamily putative drug exporter {ECO:0000313|EMBL:REE57465.1};
GN   ORFNames=A8990_15411 {ECO:0000313|EMBL:REE57465.1};
OS   Paenibacillus taihuensis.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX   NCBI_TaxID=1156355 {ECO:0000313|EMBL:REE57465.1, ECO:0000313|Proteomes:UP000256304};
RN   [1] {ECO:0000313|EMBL:REE57465.1, ECO:0000313|Proteomes:UP000256304}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 1.10966 {ECO:0000313|EMBL:REE57465.1,
RC   ECO:0000313|Proteomes:UP000256304};
RA   Whitman W.;
RT   "Genomic Encyclopedia of Type Strains, Phase III (KMG-III): the genomes of
RT   soil and plant-associated and newly described type strains.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC       (TC 2.A.6) family. MmpL subfamily. {ECO:0000256|ARBA:ARBA00010157}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:REE57465.1}.
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DR   EMBL; QTTN01000054; REE57465.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3D9Q3P2; -.
DR   Proteomes; UP000256304; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR004869; MMPL_dom.
DR   InterPro; IPR000731; SSD.
DR   PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR   PANTHER; PTHR33406:SF6; MEMBRANE PROTEIN SCO0839-RELATED; 1.
DR   Pfam; PF03176; MMPL; 2.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   PROSITE; PS50156; SSD; 2.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        199..217
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        224..245
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        257..276
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        297..321
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        333..356
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        406..426
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        562..581
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        588..612
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        624..646
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        667..692
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        698..722
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          250..354
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
FT   DOMAIN          591..719
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
SQ   SEQUENCE   745 AA;  80379 MW;  7BA81DC7A5B31E03 CRC64;
     MKNVMRAVSG KWGRWIIVVA WTLAVVLLQI GLPKADELKN DALGNFSSNK PSVQAEQLIK
     EQFPAGAGIP ALLTWHRQSG LSENDLSNMQ ALAKELAANP LPHQVGVVPL DQLPLPALKQ
     QLSEDQTTFV QTILFDKNVD SKGLKDGLTA LEKQTDAIFT ADSHPFQAEV NDPSALSVRA
     TGPVGIAVDA TELFSSADVS LLLATVLLVL VFLLLIYRSP VLALIPLIAV GFVYEAITPL
     LGWMAEQGWI EFDSQSLSIM TVLLFGAGTD YCLFLITKYR SALKLTADKF AALKHAFGSS
     AGAIAMSGLT VVFSLLVLLM AEFGSIRRFA IPFSLAIFIM MIASLTLVPA FLALLGRASF
     FPFIPRTPEM EIDRAKKKGK LLPVLEPKVS LGARLGESVT RRPKQITVIS TIILLICVFF
     ATQIKYTFDT LSSFPSDSAS REGFTLIADH FNAGELAPVQ VIVQTDGKAA VENVRETLAG
     LPFVKKVSEP AAGAKDPSLQ SYNVELATNP YSMEAISHIP NIRQAAEQAL TGAGLPDVQD
     KVWIGGQTAE QFDTKETTNK DAAVIIPVII ALIALLLLAY LRSITAMLYL IATVLLSYFS
     ALGLGWLVLH YLLGADALQG LIPLYAFVFI VALGEDYNIF MISSIWKKAR HMPLKQAVKE
     GVAETSSVIS SAGLILAGTF AVLATLPIQV LVQFGTVTAI GVLLDTFIVR PFLVPAITVL
     LGRHSFWPAS AKLPQTSEQQ AQHSS
//