ID A0A3D9SFZ1_9ACTN Unreviewed; 854 AA.
AC A0A3D9SFZ1;
DT 16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT 16-JAN-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=DNA-binding SARP family transcriptional activator {ECO:0000313|EMBL:REE94809.1};
GN ORFNames=DFJ69_0174 {ECO:0000313|EMBL:REE94809.1};
OS Thermomonospora umbrina.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Thermomonosporaceae; Thermomonospora.
OX NCBI_TaxID=111806 {ECO:0000313|EMBL:REE94809.1, ECO:0000313|Proteomes:UP000256661};
RN [1] {ECO:0000313|EMBL:REE94809.1, ECO:0000313|Proteomes:UP000256661}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43927 {ECO:0000313|EMBL:REE94809.1,
RC ECO:0000313|Proteomes:UP000256661};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:REE94809.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QTTT01000001; REE94809.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3D9SFZ1; -.
DR OrthoDB; 4336084at2; -.
DR Proteomes; UP000256661; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR35807:SF1; TRANSCRIPTIONAL REGULATOR REDD; 1.
DR PANTHER; PTHR35807; TRANSCRIPTIONAL REGULATOR REDD-RELATED; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS51755; OMPR_PHOB; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU01091}; Reference proteome {ECO:0000313|Proteomes:UP000256661}.
FT DOMAIN 1..92
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT DNA_BIND 1..92
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
FT REGION 252..276
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 420..453
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 519..548
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 854 AA; 92406 MW; 0A74898FF0ADE0C4 CRC64;
MRFNLLGPLE VIKDDVPVPL GGLHRRAALG LLLLHPNAVV ATADLVRALW DDDPPATARK
MVQNAVAALR DVLAAEERVS LRTVAPGYML RLDPHRIDLA DFRDLVRDGR TAFRAEAWDT
AARHLREALG LWRGPVLADL SEIAAAWPEP AALQEERLTA LEDCAEAELA LGLHRELLGE
LGAVAEAEPA RERLCGLVML ALYRCGQQAE ALAAFHRTRT VLVEEFGLDP APELHRLQRA
ILAQDPDLLV PASKAAPAPA PPAPPRERSK RPMAERRHAS VVLVEARVNA DTDDPERVDE
VLTEVDRIID AEAAHFGGLV RGPLGPYRLV VFGVPRAHGD DAARAIGAAL AIRRRLGTAR
PATARLAVAT GEVLAVYRDE HDAEPAELTG AVLDACRRML AHARPDGVRV CDRTRRAAGR
PFGRRAGDPV SGWNVTDDRP PAVPPPPNPP FVGREKERER LWELLDETLR ERRSHLVTVV
GEPGIGKSRL VSEFGREVRE RVGAVRVVSG DAASLGIARP DPWRPGCPAD RPASEASSDG
ASGPGPHRLD VLAARTPLVA VVEDLHRTPA AFLDLVTGMH ERPDRGPLLV IATTRPERPI
DAAPDASAIV LGPLADTEIT AMAGTLSPDL LPLIGGNPLF AQEYARLPPH RPAGPPPIPP
RVRDLLTVRL DALPVAERLV LRSVAVFEPA ASAEGVAAVS ERSADDVAAL LGILERKGVL
CRTPAGHAFR QALLRAVAYA QLPRKHRIVM HRRAAAWISG LPADQGDRLV HHHRQMIALA
ANDDRSIAVL TEQANRALTD AGHRAGMAGE HHVAARCYQG ALELSHPAPV PDRQRLRSLY
RQSLRRVGSE ARVR
//
