ID   A0A3D9SHJ7_9ACTN        Unreviewed;       346 AA.
AC   A0A3D9SHJ7;
DT   16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT   16-JAN-2019, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Fatty acid desaturase {ECO:0000313|EMBL:REE95379.1};
GN   ORFNames=DFJ69_0766 {ECO:0000313|EMBL:REE95379.1};
OS   Thermomonospora umbrina.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Thermomonosporaceae; Thermomonospora.
OX   NCBI_TaxID=111806 {ECO:0000313|EMBL:REE95379.1, ECO:0000313|Proteomes:UP000256661};
RN   [1] {ECO:0000313|EMBL:REE95379.1, ECO:0000313|Proteomes:UP000256661}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 43927 {ECO:0000313|EMBL:REE95379.1,
RC   ECO:0000313|Proteomes:UP000256661};
RA   Klenk H.-P.;
RT   "Sequencing the genomes of 1000 actinobacteria strains.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the fatty acid desaturase type 1 family.
CC       {ECO:0000256|ARBA:ARBA00009295}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:REE95379.1}.
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DR   EMBL; QTTT01000001; REE95379.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3D9SHJ7; -.
DR   OrthoDB; 104711at2; -.
DR   Proteomes; UP000256661; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016717; F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; IEA:UniProt.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProt.
DR   CDD; cd03506; Delta6-FADS-like; 1.
DR   InterPro; IPR005804; FA_desaturase_dom.
DR   InterPro; IPR012171; Fatty_acid_desaturase.
DR   PANTHER; PTHR19353:SF19; DELTA(5) FATTY ACID DESATURASE C-RELATED; 1.
DR   PANTHER; PTHR19353; FATTY ACID DESATURASE 2; 1.
DR   Pfam; PF00487; FA_desaturase; 1.
DR   PIRSF; PIRSF015921; FA_sphinglp_des; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000256661};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        39..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        65..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        104..121
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        169..189
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        201..219
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          65..323
FT                   /note="Fatty acid desaturase"
FT                   /evidence="ECO:0000259|Pfam:PF00487"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   346 AA;  38215 MW;  2E37B6D7394378F5 CRC64;
     MPQTLAPAPA EAPARAPGSD FAPLSRQVRD SGLLDRRRGY YSAIIALNLL ATAGIWVGVA
     LADGAWWAVA LALPAAMISA RTGFLGHDAG HRQIARSARA NRWLGLLFGN VISGMSSAWW
     TDKHNRHHAN PNHVDKDPDV ASGVLVWTAE QAADRRRLAA WMTRHQAGLF FPLLTLEGWW
     LKVAGLLDLR SRSWRERLLE GGLMAVHLVG YFALAFTLMP TAQAITFVLV HQALFGLHLG
     SVFAPNHKGM AMPGPDERWD HLRRQVLTSR NIRRGVVTDW MMGGLNYQIE HHLFPSIPRC
     NLSRLQPLVR EHCAKVGLPY AETSALESYA QALGHMHEVG ESLRAA
//