ID   A0A3D9SMK9_9ACTN        Unreviewed;       604 AA.
AC   A0A3D9SMK9;
DT   16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT   16-JAN-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Carnitine O-acetyltransferase {ECO:0000313|EMBL:REE95650.1};
GN   ORFNames=DFJ69_1059 {ECO:0000313|EMBL:REE95650.1};
OS   Thermomonospora umbrina.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Thermomonosporaceae; Thermomonospora.
OX   NCBI_TaxID=111806 {ECO:0000313|EMBL:REE95650.1, ECO:0000313|Proteomes:UP000256661};
RN   [1] {ECO:0000313|EMBL:REE95650.1, ECO:0000313|Proteomes:UP000256661}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 43927 {ECO:0000313|EMBL:REE95650.1,
RC   ECO:0000313|Proteomes:UP000256661};
RA   Klenk H.-P.;
RT   "Sequencing the genomes of 1000 actinobacteria strains.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the carnitine/choline acetyltransferase family.
CC       {ECO:0000256|ARBA:ARBA00005232, ECO:0000256|RuleBase:RU003801}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:REE95650.1}.
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DR   EMBL; QTTT01000001; REE95650.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3D9SMK9; -.
DR   Proteomes; UP000256661; Unassembled WGS sequence.
DR   GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR   Gene3D; 3.30.559.70; Choline/Carnitine o-acyltransferase, domain 2; 1.
DR   InterPro; IPR000542; Carn_acyl_trans.
DR   InterPro; IPR023213; CAT-like_dom_sf.
DR   InterPro; IPR039551; Cho/carn_acyl_trans.
DR   InterPro; IPR042231; Cho/carn_acyl_trans_2.
DR   PANTHER; PTHR22589; CARNITINE O-ACYLTRANSFERASE; 1.
DR   Pfam; PF00755; Carn_acyltransf; 1.
DR   SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR   PROSITE; PS00440; ACYLTRANSF_C_2; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW   ECO:0000256|RuleBase:RU003801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000256661};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003801}.
FT   DOMAIN          21..591
FT                   /note="Choline/carnitine acyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF00755"
FT   ACT_SITE        320
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR600542-1"
SQ   SEQUENCE   604 AA;  66261 MW;  3D5870B541E1C1E8 CRC64;
     MNTLHEPSPR TFGNEHALPR VPLPALEETC DRFLDWCAPL LTEEELVATR DEVTAFLRPD
     GPGRRLHAAL AEYDSREDVH SWLDTFWPYR YLGRRDRIAL NANFIFLFKD VEQSQTERAA
     GLIAAAVDFK LLLDEERIPP AVQRGTVLSM EQNKYLFSAT RIPGAVQDTV RVPYTEEWPG
     PSPARHIIVL YRGNMFRLDV IGQDGRPHTL DDLQAGLGAI IKSGAARADR DTSVGHLTTK
     ARAEWAASRE ALLALDPANA AALDTVETAL FCICLEDVAL QDDLAACDRL LHGDSGNRWF
     DKAVSLIVFE DGRAGINVEH CGLDGTTILS FVDALLDTSA EEHSARSGAV SQGLPAVEAV
     EFVLDDALRA DVAAAADAFA AYAEATASTI VSFDDFGGNT AKQLKTSPDA FVQMAYQLAH
     KRAKGITGAT YESIATRQYR HGRTEAMRVV TPEALAFVAA MEDPGADPGA RRAAFRAAAE
     AHVRRAKECQ SGQAPEQHLW ELQLIAKRRG EELGVTEPLP LYESPGWVIM RDDYLSTSSA
     PSKNIQYFGF GSTSEQCIGV AYVLLPDRFN VYLSTPRPVA DAMHTFAGHL RDTVRELREL
     LAAE
//