ID   A0A3D9ST03_9ACTN        Unreviewed;       527 AA.
AC   A0A3D9ST03;
DT   16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT   16-JAN-2019, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Fatty-acyl-CoA synthase {ECO:0000313|EMBL:REE97610.1};
GN   ORFNames=DFJ69_3083 {ECO:0000313|EMBL:REE97610.1};
OS   Thermomonospora umbrina.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Thermomonosporaceae; Thermomonospora.
OX   NCBI_TaxID=111806 {ECO:0000313|EMBL:REE97610.1, ECO:0000313|Proteomes:UP000256661};
RN   [1] {ECO:0000313|EMBL:REE97610.1, ECO:0000313|Proteomes:UP000256661}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 43927 {ECO:0000313|EMBL:REE97610.1,
RC   ECO:0000313|Proteomes:UP000256661};
RA   Klenk H.-P.;
RT   "Sequencing the genomes of 1000 actinobacteria strains.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:REE97610.1}.
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DR   EMBL; QTTT01000001; REE97610.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3D9ST03; -.
DR   OrthoDB; 3443462at2; -.
DR   Proteomes; UP000256661; Unassembled WGS sequence.
DR   GO; GO:0016877; F:ligase activity, forming carbon-sulfur bonds; IEA:UniProt.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR   PANTHER; PTHR43767:SF1; NONRIBOSOMAL PEPTIDE SYNTHASE PES1 (EUROFUNG)-RELATED; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000256661}.
FT   DOMAIN          15..377
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          438..513
FT                   /note="AMP-binding enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13193"
SQ   SEQUENCE   527 AA;  56660 MW;  6D0F34573391332E CRC64;
     MARTYNLADL LELLAEAGPD RPAVVAGEER RSYRELNERA SKVGHHLAAA GVKAGEHVAI
     LSWNRVEWME TFLGIFKIRA VPVPVNYRYV AGELHHVLAD SDSVALIAER SLLEKVQEIR
     GDLPKLRHVI VLEDGGANEV PDSVEFETAI KDAPSTDDFP ERSNDDRYIM YTGGTTGYPK
     GVEWRCEDIF FGAMGGGNVL GDPITSPDAI RANAEQPAMA VLDCAPVMHG AGQWVACMGL
     FSGAKVVLYT DHNFVPADVL HLLAEEEANV LFVVGDVMAR PLAKELAKGG YDTSSLFAIG
     SGGAPLTEGA KDAILAELPS MMFLDNYGAS ETGACGPSIG GKEGTARFMM KPGITVLDDD
     LKQVRPGEIG RLARSGHIPV GYYNDPAKTA STFFTDAEGV RWSVPGDFAS LEEDGSIVLL
     GRGSLVINTG GEKVYPEEVE VALKDHPDVY DCVVVGLPDE RFGQSVAAVV APRAGAAPTL
     EELTEHCRGR LAGYKLPRRL ELVPEVQRTA VGKSDYKWAK SVLAVKD
//