ID A0A3D9T458_9ACTN Unreviewed; 1303 AA.
AC A0A3D9T458;
DT 16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT 16-JAN-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=ATP-dependent helicase HrpA {ECO:0000313|EMBL:REF00036.1};
GN ORFNames=DFJ69_5558 {ECO:0000313|EMBL:REF00036.1};
OS Thermomonospora umbrina.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Thermomonosporaceae; Thermomonospora.
OX NCBI_TaxID=111806 {ECO:0000313|EMBL:REF00036.1, ECO:0000313|Proteomes:UP000256661};
RN [1] {ECO:0000313|EMBL:REF00036.1, ECO:0000313|Proteomes:UP000256661}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43927 {ECO:0000313|EMBL:REF00036.1,
RC ECO:0000313|Proteomes:UP000256661};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:REF00036.1}.
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DR EMBL; QTTT01000001; REF00036.1; -; Genomic_DNA.
DR OrthoDB; 9805617at2; -.
DR Proteomes; UP000256661; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR CDD; cd17989; DEXHc_HrpA; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR024590; HrpA_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010222; RNA_helicase_HrpA.
DR NCBIfam; TIGR01967; DEAH_box_HrpA; 1.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF11898; DUF3418; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:REF00036.1};
KW Hydrolase {ECO:0000313|EMBL:REF00036.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000256661}.
FT DOMAIN 83..246
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 280..443
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 1303 AA; 147827 MW; 6F4D536451297E65 CRC64;
MRSPLAELRQ RLPELMLRDQ HRLRRRIDAA RGLRDRDRLA EVVARLAADV DRAQARVASR
RAAVPTVSYP AELPVSQRKD DIAAAIRDHQ VVIVAGETGS GKTTQIPKIC LELGRGVLGT
IGHTQPRRLA ARTVADRIAE EIGTPLGETV GFKVRFTDTS GDDTLVKLMT DGILLAEVQT
DRLLRQYDTL IIDEAHERSL NIDFLLGYLK EILPRRPDLK VIITSATIDP ERFSRHFDDA
PIVEVSGRTY PVEVRYRPIV DPEDPDADPD RDQVQAIMDA VDELALEARG DVLVFLSGER
EIRDTADALT KRGLRDTEIL PLYARLSAAE QHRVFQRHRG RRIVLATNVA ETSLTVPGIK
YVIDPGTARI SRYSHRLKVQ RLPIEAISQA SANQRKGRCG RVSEGICIRL YSEEDFLSRP
EFTDPEILRT NLASVILQMT SLGLGDIAAF PFVEPPDRRN IKDGVDLLHE LGAFDPAEKD
PRKRMTPLGR KLAQLPVDPR LARMVLEADD HGCVREVLVI ASALSIQDPR ERPADKQQAA
DERHRRFADP TSDFLAYLNL WNHLRDKQKE LSGGQFRRMC KSEFLHYLRV REWQDLHGQL
KQVARGLGVT VNTADAPPEN VHRALLAGLL SHVGLMDPEK REYLGARGAR FALFPGSGLF
KKPPRWVMSA ELVETSRLWA RVNARIEPEW IEPLAQHLVK RTYSEPHWSK KQGAAMAYER
VTLYGVPIVT QRRVQYGRID PELARELFIR HALVGGEWET HHRFFHQNRA LLEEVEDLEH
RARRRDILVD DETLFDFYDE RLPADAISVR HFDVWWKQAR RDTPDLLNFE RRMLINAGAD
EVREDDYPDA WRQGPLKLAL TYRFEPGADA AGTDGVTVHV PLQVLNQVGP DGFDWQVPGL
RTELVTELIR SLPKQLRVNF VPAPDVARRV LQRVSPRGEP LLDALERELR AMTGVTVARE
SWDPSRLPGH LKMTFRVVDD RDRTVAEGKD LDELKRRLKG EMRGTLSTVA QKDGVERAGL
RTWDVGTLPQ TFQRSRAGYE VKAYPALTDE GDTVAVRMYE TPAEQRHAMW RGTRRLVLLN
APSPVKFLQG RLTNQGKLAL SHSPHGSVAA LFDDCVTAAA DKLIAEAGGP AWDEEGFTKL
YDHVRSDLAD TAAAVVTHVE RILKTSHDLD RRLRGTGSLT LVPSLTDLRA QLDDLVSPGF
VTATGWRRLP DLLRYLRAME ARLDKLPENP NRDRLLMQQV ERMRQEYLAL LHRLPPARRD
EDAVRQVRWM IEELRVSLFA QRLGTRYPVS DKRILKAIAQ ITA
//
