ID A0A3E0DKL0_9GAMM Unreviewed; 366 AA.
AC A0A3E0DKL0;
DT 16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT 16-JAN-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Multidrug efflux system membrane fusion protein {ECO:0000313|EMBL:REG83306.1};
GN ORFNames=DFP81_106166 {ECO:0000313|EMBL:REG83306.1};
OS Marinomonas pollencensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Oceanospirillaceae; Marinomonas.
OX NCBI_TaxID=491954 {ECO:0000313|EMBL:REG83306.1, ECO:0000313|Proteomes:UP000256542};
RN [1] {ECO:0000313|EMBL:REG83306.1, ECO:0000313|Proteomes:UP000256542}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT 7375 {ECO:0000313|EMBL:REG83306.1,
RC ECO:0000313|Proteomes:UP000256542};
RA Whitman W.;
RT "Genomic Encyclopedia of Type Strains, Phase III (KMG-III): the genomes of
RT soil and plant-associated and newly described type strains.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:REG83306.1}.
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DR EMBL; QUNG01000006; REG83306.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3E0DKL0; -.
DR OrthoDB; 9806939at2; -.
DR Proteomes; UP000256542; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF29; BLR2860 PROTEIN; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000256542};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 85..283
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT REGION 34..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 366 AA; 39248 MW; 7E26F3EA96A59B7F CRC64;
MELKSKIGPL VAIIITVAAV LWIYAGGHGI TASQHDSPTN TNESNSNNAE HTSLSNQKHS
VQVTNIQAQS INLYLALSGQ TLADKILTLT NSYPGEVVKL YSTKGDFLEQ GAPILQIDTR
VLKTQIRETS ALIKQRNIEL NGLNKLKDIN LTSHVRLAEA ETNLASALTS AKSLAIDLEN
ATVTAPFSGV LNTLDIEKGQ MLSDDSAIGT LVSLNPLRIQ VTIPQNKIHH IHLGTQGKVH
LATGLETTGK VSYISRQANT ESRSINVELL IDNPNHSIAA GLTADVTFAL SQQKAQALSP
ALLTLDDDGN TAVKTVDSQS KVVSYPVNIV KSERDKVWVS GLPSEVNLIT VGQGFVNDGD
IVDIHH
//
