ID A0A3E0ECS0_9FLAO Unreviewed; 636 AA.
AC A0A3E0ECS0;
DT 16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT 16-JAN-2019, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=acetate--CoA ligase {ECO:0000256|ARBA:ARBA00013275};
DE EC=6.2.1.1 {ECO:0000256|ARBA:ARBA00013275};
GN ORFNames=C8P67_11117 {ECO:0000313|EMBL:REG96045.1};
OS Flavobacterium aquicola.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=1682742 {ECO:0000313|EMBL:REG96045.1, ECO:0000313|Proteomes:UP000257136};
RN [1] {ECO:0000313|EMBL:REG96045.1, ECO:0000313|Proteomes:UP000257136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 100880 {ECO:0000313|EMBL:REG96045.1,
RC ECO:0000313|Proteomes:UP000257136};
RA Goeker M.;
RT "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT (KMG-II): from individual species to whole genera.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:REG96045.1}.
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DR EMBL; QUNI01000011; REG96045.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3E0ECS0; -.
DR OrthoDB; 9778383at2; -.
DR Proteomes; UP000257136; Unassembled WGS sequence.
DR GO; GO:0003987; F:acetate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0016208; F:AMP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0019427; P:acetyl-CoA biosynthetic process from acetate; IEA:InterPro.
DR CDD; cd05966; ACS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR011904; Ac_CoA_lig.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR02188; Ac_CoA_lig_AcsA; 1.
DR PANTHER; PTHR24095; ACETYL-COENZYME A SYNTHETASE; 1.
DR PANTHER; PTHR24095:SF14; ACETYL-COENZYME A SYNTHETASE 1; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 12..68
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 70..462
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 519..598
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 636 AA; 71588 MW; 6AF24808E330F642 CRC64;
MSYFKIDSLE QYFKHYNKSI REPRKFWGKI AEENFTWYQY WDKVVDFNMA DAEVKWFVDA
KVNITKNCID RHLAKKGDKT AIIFEPNDPS EQALHISYNE LYERVSKMAN VLREQGINKG
DRVCIYLPMI PELAVAVLAC ARIGAIHSVV FAGFSASAVA SRINDSQCKM VITSDGGYRG
NKTIDLKGIV DEALQNCPSV TSVLVAKRTN AEIQMKAGRD QWLAPLLDNA LNNSVAEIMD
AEDPLFILYT SGSTGKPKGM VHTTAGYMVY TAYTFKNVFN YEENDIFWCT ADIGWITGHS
YILYGPLLNG ATTVIYEGIP SYPDFSRFWE TIEKHKVTQF YTAPTAIRAL AKENLSYVQR
FPLKSLKVIG SVGEPINEEA WHWYNDHVGG KRCPVVDTWW QTETGGIMIA PLAFTTPTKP
TYATLPLPGI QPVLMDDKRN EIEGNQVVGS LCIKFPWPGI ARTIWGDHQR YKDTYFSTFP
GKYFTGDGAL RDEVGYYRIT GRVDDVVIVS GHNLGTAPIE DAINEHPAVA ESAIVGFPHD
IKGNALYGYV ILKESGEYRD RDNLSKEINQ HIADHIGPIA KLDKIQYVTG LPKTRSGKIM
RRILRKIAEG DYSNFGDITT LLNPEIVEEI VKGRIV
//
