ID A0A3E0EQW9_9FLAO Unreviewed; 597 AA.
AC A0A3E0EQW9;
DT 16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT 16-JAN-2019, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=CIC family chloride channel protein {ECO:0000313|EMBL:REG99546.1};
GN ORFNames=C8P67_104164 {ECO:0000313|EMBL:REG99546.1};
OS Flavobacterium aquicola.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=1682742 {ECO:0000313|EMBL:REG99546.1, ECO:0000313|Proteomes:UP000257136};
RN [1] {ECO:0000313|EMBL:REG99546.1, ECO:0000313|Proteomes:UP000257136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 100880 {ECO:0000313|EMBL:REG99546.1,
RC ECO:0000313|Proteomes:UP000257136};
RA Goeker M.;
RT "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT (KMG-II): from individual species to whole genera.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:REG99546.1}.
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DR EMBL; QUNI01000004; REG99546.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3E0EQW9; -.
DR OrthoDB; 9812438at2; -.
DR Proteomes; UP000257136; Unassembled WGS sequence.
DR GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR CDD; cd00400; Voltage_gated_ClC; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR PANTHER; PTHR43427; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR PANTHER; PTHR43427:SF6; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
DR PROSITE; PS51371; CBS; 2.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 25..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 64..86
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 164..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 277..295
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 327..351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 388..411
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 417..434
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 473..529
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 538..593
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 597 AA; 65538 MW; A5182886F6528072 CRC64;
MIKKFFSKIE YLLALSQSAL TPKQFIFLSS VIVGISSALA VIVLKTFAHW VFRFATYVTI
HTNFFNVGIV KIMLPVIGIM LTVFVVNRFL GGSIEKGTSQ ILYAVAKKAS IIPRKQMYAQ
IATSSLTVGL GGSAGLESPI VITGAAFGSN YAQKYKLSYK DRTLLIGCGV AAGIGAAFNA
PIAGVLFAVE VLLVDVSISA FTPIMIAAAT GALVSAIALD ETILLNFPTR QTFDYHNIFY
YIFLGVFTGF IGVYYARNFQ RIEHYFAHMR LSSYKKAFFG ASILALMIFI FPTLFGEGYE
TIRTLSESDP GQLLDDTLFK SFRNNNWALL AFVGCSFMLK AFASGITLGS GGNGGNFAPA
LFLGSYVGFF FSKLLNLTGL THLPISNFTV VGMSGILSGL FHAPLTAIFL IAEITGGYGL
MIPLMIVASI SYAISKRFEV HSLDVKNLAK KGHAFTSNKD TNVLSTLDTN SIIQTDYLTI
SPDENLEKLV DLISHSNQVI FAVVSLDKKL LGIVHFNDIR EIIFNPYRVK YTLIKEIMVQ
PVAVVHPTNS MEIVMDKFET TKKAFLPVIR DDKYYGFISK SVALEAYRTK LKSMTIE
//
