ID A0A3E0EUM9_9FLAO Unreviewed; 494 AA.
AC A0A3E0EUM9;
DT 16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT 16-JAN-2019, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=Alpha-L-fucosidase {ECO:0000313|EMBL:REH01524.1};
GN ORFNames=C8P67_1012 {ECO:0000313|EMBL:REH01524.1};
OS Flavobacterium aquicola.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=1682742 {ECO:0000313|EMBL:REH01524.1, ECO:0000313|Proteomes:UP000257136};
RN [1] {ECO:0000313|EMBL:REH01524.1, ECO:0000313|Proteomes:UP000257136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 100880 {ECO:0000313|EMBL:REH01524.1,
RC ECO:0000313|Proteomes:UP000257136};
RA Goeker M.;
RT "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT (KMG-II): from individual species to whole genera.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-
CC 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the
CC carbohydrate moieties of glycoproteins.
CC {ECO:0000256|ARBA:ARBA00004071}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:REH01524.1}.
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DR EMBL; QUNI01000001; REH01524.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3E0EUM9; -.
DR OrthoDB; 1095333at2; -.
DR Proteomes; UP000257136; Unassembled WGS sequence.
DR GO; GO:0004560; F:alpha-L-fucosidase activity; IEA:InterPro.
DR GO; GO:0006004; P:fucose metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR016286; FUC_metazoa-typ.
DR InterPro; IPR031919; Fucosidase_C.
DR InterPro; IPR000933; Glyco_hydro_29.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR10030; ALPHA-L-FUCOSIDASE; 1.
DR PANTHER; PTHR10030:SF46; ALPHA-L-FUCOSIDASE-RELATED; 1.
DR Pfam; PF01120; Alpha_L_fucos; 1.
DR Pfam; PF16757; Fucosidase_C; 1.
DR PIRSF; PIRSF001092; Alpha-L-fucosidase; 2.
DR SMART; SM00812; Alpha_L_fucos; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 4: Predicted;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..494
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017643504"
FT DOMAIN 407..490
FT /note="Alpha-L-fucosidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16757"
FT SITE 326
FT /note="May be important for catalysis"
FT /evidence="ECO:0000256|PIRSR:PIRSR001092-1"
SQ SEQUENCE 494 AA; 57202 MW; 8D3F06653E15E0F4 CRC64;
MKKRIAIIAL LFSAQLFSQA IYEDERYVPE TDPLVLKNLE EWQGKKFGLL MHWGTYSQWG
IVESWSICPE DYGWCERKKE SNPANYNDYV KEYEGLKKTF NPVKFDPSKW AKAAKYAGMK
YMVFTTKHHD GFNMFDTKYS DYKVTDKDCP FSSNPKSNIA KEVFNAFRNE NLIVGAYFSK
PDWHNENYWD PYFPPFDRNV NYDPTLYPEK WKKYVDFTHN QILELLTDYG KVDILWLDGG
WVKKRDLQNI KENYEEKFAE NESKNGFIKH RVVDQDPKMD ELVVEARQKQ PGLIVVDRAV
HGKNQNYLTP ENRVPEKTLP YPWESCITSG GGWSYTPDAT YLTGRQGIHM LIDVVAKGGN
LLLNVAPSPE GEWQQGAYDL LTAYGDWMKV NSTAIYNTKP IAPYKENNIC MTQNKEGNVF
LFYLAKEGET RIPAEVVVKS ISPKKGTKIT MLGSKTSLKW TKESEGFKVI IPESLRQNLP
AKEAWTLKIE AVNR
//
