ID   A0A3E0U5J3_9GAMM        Unreviewed;      1045 AA.
AC   A0A3E0U5J3;
DT   16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT   16-JAN-2019, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=AcrB/AcrD/AcrF family protein {ECO:0000313|EMBL:REL31837.1};
GN   ORFNames=DXX94_14540 {ECO:0000313|EMBL:REL31837.1};
OS   Thalassotalea euphylliae.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC   Colwelliaceae; Thalassotalea.
OX   NCBI_TaxID=1655234 {ECO:0000313|EMBL:REL31837.1, ECO:0000313|Proteomes:UP000256899};
RN   [1] {ECO:0000313|Proteomes:UP000256899}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H3 {ECO:0000313|Proteomes:UP000256899};
RA   Summers S., Rice S.A., Freckelton M.L., Nedved B.T., Hadfield M.G.;
RT   "Thalassotalea euphylliae genome.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:REL31837.1}.
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DR   EMBL; QUOT01000001; REL31837.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3E0U5J3; -.
DR   Proteomes; UP000256899; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR   Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR   Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   InterPro; IPR000731; SSD.
DR   PANTHER; PTHR32063; -; 1.
DR   PANTHER; PTHR32063:SF0; SWARMING MOTILITY PROTEIN SWRC; 1.
DR   Pfam; PF00873; ACR_tran; 1.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   PROSITE; PS50156; SSD; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000256899};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        336..356
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        363..383
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        389..409
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        430..454
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        466..488
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        524..542
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        853..872
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        879..903
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        909..930
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        958..979
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        985..1009
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          880..1011
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
FT   REGION          1015..1045
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1030..1045
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1045 AA;  113513 MW;  9C9B4C8D9652DD2E CRC64;
     MNLTRAALKN PAAIIVVAAL IMVFGLLSVT KLPIQLTPDI EQPQISIFTG WRSAAPEEME
     SVIIEPLENA VKNTQGVTKV TTFIQRGSGN ITLTFDVGAD MQKAMLEVIN NLNQAPPLPL
     DAIEPVVSAG GGRGGPQTAS LLIKTLPDNP NRDLGQYQKL IEDVVKPRFA RIPGLAQVNL
     ASHRPRELRV TFDPLRAASL GLPIADISAT IARANDVSAG TADVGRRQYT VRFAGKYDVD
     NLTEMIVGYS GNRPIYLKDI ATVENTLVDR NGFSLRSGQP AYYFTLTRQN DANTVALLDE
     INVAIKELNE GPMRAAGLTI DLSFDSSVHI RNALTLVKSN LGLGVLLALM ILWLFLRGMR
     NTLIIATTIP ISLFVSFVAL SIFERSLNVI SLAGLAFSVG LVLDAAIIVQ ENIVRMRTNG
     LDNHKAVLRG AMQVTGALFA STATSVAIFL PILFMEGIEG QLFSDLALTL SIAVIASLVT
     AITVLPIASK FWLKNVKESD PYDHYWQKLT NLVMRLTNSR IKRYSWVGVL LGGSLVISVT
     MLPKTDFMPR APIDGFFYSL NMPPGGNVDF VENEMAALIK SRLAPYLAGE QQPKIKSYNF
     YSNGSANTGG FIYADDPTRV EELMNIVRNE IFKGLPDTQA FLFRGSMINV SGGGNGRTVD
     IDISGPDIEA LMSVAQVGID AINQNMANTT AFPMPSLSLA EPELKLTPDD QRITQAGLTR
     HDVANAVRAF TSGLFINEYF DGNDRVNVIL RADQWQTPDE LAALPVYSPF AGIQTIGELT
     QIERTAGPTQ LRRVDGKRTI SIQVTPPADM SLEEALAILS EKVVPAMQID LPDDSSILLS
     GNANKMAAAI QDMIQNFVLA LVILFLLMTA LFKSAKDSLL VLMVMPLAVA GGVLALNGLN
     LFTYQSLDLL TMIGFIILLG LVVNNAILLV DQTRQAEREG LTRRRAVAQA VRVRARPVYM
     STLTSLFGML PLMLMPGVGS EIYRGLATVI VGGMMVSALF TLVLFPALLR FNESDSKVDG
     SDDENNTNDN IEPLHPTPQL KISNR
//