ID A0A3E0VF83_9MICO Unreviewed; 499 AA.
AC A0A3E0VF83;
DT 16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT 16-JAN-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=AAA domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=B7R54_03085 {ECO:0000313|EMBL:RFA08319.1};
OS Subtercola boreus.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Subtercola.
OX NCBI_TaxID=120213 {ECO:0000313|EMBL:RFA08319.1, ECO:0000313|Proteomes:UP000256486};
RN [1] {ECO:0000313|EMBL:RFA08319.1, ECO:0000313|Proteomes:UP000256486}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K300 {ECO:0000313|EMBL:RFA08319.1,
RC ECO:0000313|Proteomes:UP000256486};
RA Cho Y.-J., Cho A., Kim O.-S., Lee J.-I.;
RT "Comparative genome analysis of Subtercola boreus.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-
CC [protein]; Xref=Rhea:RHEA:10596, Rhea:RHEA-COMP:10136, Rhea:RHEA-
CC COMP:10137, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:46858,
CC ChEBI:CHEBI:82620, ChEBI:CHEBI:456216;
CC Evidence={ECO:0000256|ARBA:ARBA00001074};
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the etk/wzc family.
CC {ECO:0000256|ARBA:ARBA00008883}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RFA08319.1}.
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DR EMBL; NBWZ01000001; RFA08319.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3E0VF83; -.
DR OrthoDB; 9812433at2; -.
DR Proteomes; UP000256486; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0045226; P:extracellular polysaccharide biosynthetic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd05387; BY-kinase; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR025669; AAA_dom.
DR InterPro; IPR003856; LPS_length_determ_N_term.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005702; Wzc-like_C.
DR NCBIfam; TIGR01007; eps_fam; 1.
DR PANTHER; PTHR32309; TYROSINE-PROTEIN KINASE; 1.
DR PANTHER; PTHR32309:SF13; TYROSINE-PROTEIN KINASE ETK-RELATED; 1.
DR Pfam; PF13614; AAA_31; 1.
DR Pfam; PF02706; Wzz; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000256486};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Tyrosine-protein kinase {ECO:0000256|ARBA:ARBA00023137}.
FT TRANSMEM 175..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 3..88
FT /note="Polysaccharide chain length determinant N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02706"
FT DOMAIN 273..417
FT /note="AAA"
FT /evidence="ECO:0000259|Pfam:PF13614"
FT REGION 463..499
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 470..484
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 499 AA; 53210 MW; 3791336DABAE7AA0 CRC64;
MQLQDILRVL QRSWILIVGL TVLGLLAAGA ALAVTAPQYQ STSRLFVSTQ ATDNASNALQ
GSTYTQNRMI SYSHLVVQPI VLDPVIAALG LDLTADQLAS HVSADVITDS LILEVTVTEP
SAQQSADIAN AIATQLVTTI TTQIEDPGDG TKPLIAVSII ADASVATSPT SPLPWLYLLV
GGVGGLLLSV GLAFLIAGFD NRVRSIDDLK RLTDLPVLGH FPRQNTAREK PLLLADDMMS
QRAESFRALR TNLQYFDLAT TNQVLLFTSS IPGEGKTTTS LNLAITLAQT GKRVIYIECD
LRRPKSAKYL NIEGAVGLSD VLVSRVALDD VLQAGVVETL TILPAGSLPP NPSELLGSEQ
FASLLSSMRL LYDYVILDAP PLLAVTDAAI LSRESDGVIV VVGTSLVNRQ QVETSIDILT
QVDAHVLGVA ANFLPRRGVD AYSYYTYGYV ALSAVRDARV PGAADRSDDP SAAPADDRIS
DVAHATRRAA TSAERLTRR
//
