ID A0A3E1EZ68_9FLAO Unreviewed; 430 AA.
AC A0A3E1EZ68;
DT 16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT 16-JAN-2019, sequence version 1.
DT 24-JAN-2024, entry version 11.
DE SubName: Full=Nucleotide sugar dehydrogenase {ECO:0000313|EMBL:RFC54846.1};
GN ORFNames=DXU93_06905 {ECO:0000313|EMBL:RFC54846.1};
OS Brumimicrobium aurantiacum.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Crocinitomicaceae; Brumimicrobium.
OX NCBI_TaxID=1737063 {ECO:0000313|EMBL:RFC54846.1, ECO:0000313|Proteomes:UP000257127};
RN [1] {ECO:0000313|EMBL:RFC54846.1, ECO:0000313|Proteomes:UP000257127}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=N62 {ECO:0000313|EMBL:RFC54846.1,
RC ECO:0000313|Proteomes:UP000257127};
RA Du Z.-J., Luo H.-R.;
RT "The draft genome squence of Brumimicrobium sp. N62.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the UDP-glucose/GDP-mannose dehydrogenase
CC family. {ECO:0000256|PIRNR:PIRNR000124}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RFC54846.1}.
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DR EMBL; QURB01000003; RFC54846.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3E1EZ68; -.
DR OrthoDB; 9803238at2; -.
DR Proteomes; UP000257127; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR017476; UDP-Glc/GDP-Man.
DR InterPro; IPR014027; UDP-Glc/GDP-Man_DH_C.
DR InterPro; IPR036220; UDP-Glc/GDP-Man_DH_C_sf.
DR InterPro; IPR014026; UDP-Glc/GDP-Man_DH_dimer.
DR InterPro; IPR001732; UDP-Glc/GDP-Man_DH_N.
DR InterPro; IPR028359; UDP_ManNAc/GlcNAc_DH.
DR NCBIfam; TIGR03026; NDP-sugDHase; 1.
DR PANTHER; PTHR43491; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR PANTHER; PTHR43491:SF2; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR Pfam; PF00984; UDPG_MGDP_dh; 1.
DR Pfam; PF03720; UDPG_MGDP_dh_C; 1.
DR Pfam; PF03721; UDPG_MGDP_dh_N; 1.
DR PIRSF; PIRSF500136; UDP_ManNAc_DH; 1.
DR PIRSF; PIRSF000124; UDPglc_GDPman_dh; 1.
DR SMART; SM00984; UDPG_MGDP_dh_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52413; UDP-glucose/GDP-mannose dehydrogenase C-terminal domain; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius}; NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 320..420
FT /note="UDP-glucose/GDP-mannose dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00984"
SQ SEQUENCE 430 AA; 47451 MW; A278BC22D83499C8 CRC64;
MHTKLINREA KLAVIGLGYV GLPIALEFAR KMDVIGFDIN KDRVELMKNN IDPSKELESS
DFEGCTIEFS ANLEDLSEAT FFVIAVPTPI DGSNKPNLGP LLGASSTVGK VLKKGDYVVF
ESTVYPGCTE EDCIPVLEKE SGLNFETDFS VGYSPERINP GDKVHTLQNV VKVVSGDSAE
SLEEIAKVYE EVVEAGVHRA STIKVAEAAK IIENTQRDVN ISLINELSKI FDKLEINTYE
VLEAAGTKWN FLPFQPGLVG GHCIGVDPYY LTYKAKKVGY HAEIINSGRS VNDSMGFYIG
KQTVKKMIAQ GKNMNEAKVL IMGATFKENV SDIRNSKVID VVNELKSFSV EVDLIDPFAS
SDEMMQEYGV ALADKTGEEY DAVIVAVNHA EYARLTEDDF KKYLKDGKGV FVDIKGVFKG
QIQDLEYWSL
//
