ID A0A3E1F101_9FLAO Unreviewed; 570 AA.
AC A0A3E1F101;
DT 16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT 16-JAN-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=THUMP domain-containing protein {ECO:0000259|PROSITE:PS51165};
GN ORFNames=DXU93_00695 {ECO:0000313|EMBL:RFC55485.1};
OS Brumimicrobium aurantiacum.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Crocinitomicaceae; Brumimicrobium.
OX NCBI_TaxID=1737063 {ECO:0000313|EMBL:RFC55485.1, ECO:0000313|Proteomes:UP000257127};
RN [1] {ECO:0000313|EMBL:RFC55485.1, ECO:0000313|Proteomes:UP000257127}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=N62 {ECO:0000313|EMBL:RFC55485.1,
RC ECO:0000313|Proteomes:UP000257127};
RA Du Z.-J., Luo H.-R.;
RT "The draft genome squence of Brumimicrobium sp. N62.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RFC55485.1}.
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DR EMBL; QURB01000001; RFC55485.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3E1F101; -.
DR OrthoDB; 9809404at2; -.
DR Proteomes; UP000257127; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0034470; P:ncRNA processing; IEA:UniProt.
DR GO; GO:0009451; P:RNA modification; IEA:UniProt.
DR CDD; cd11715; THUMP_AdoMetMT; 1.
DR Gene3D; 3.30.2130.30; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR000241; RlmKL-like_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR004114; THUMP_dom.
DR PANTHER; PTHR47313; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K/L; 1.
DR PANTHER; PTHR47313:SF1; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K_L; 1.
DR Pfam; PF02926; THUMP; 1.
DR Pfam; PF01170; UPF0020; 1.
DR SMART; SM00981; THUMP; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
DR PROSITE; PS51165; THUMP; 1.
DR PROSITE; PS01261; UPF0020; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00529};
KW Transferase {ECO:0000256|ARBA:ARBA00022603}.
FT DOMAIN 45..157
FT /note="THUMP"
FT /evidence="ECO:0000259|PROSITE:PS51165"
FT REGION 382..570
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 382..441
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 461..498
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 511..570
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 570 AA; 65139 MW; D6155AE3BC8DAB6C CRC64;
MKDLVITVKT LFGFEDILKE ELNELGYDKV ETLNRAVQLN GDWEDVYRLN YHCRLAISVL
VKVKSFTIHK EEDLYKQAKK IDWPAYFDVK KTFAVKGAVF STIFTHTQYP FLVVKDAIAD
VFREKCDDVR PDVNLKSPQV MFDVYIKDRN VVISLNTSGV PLFQRGYRQE VGEAPMNEVL
AAGILRMSGW DRKSTLIDPM CGSGTIAIEA ALWAANIPAM IERNHFAFKN FKSFDAEAWE
KVKAEGNSRP IKLGFDILAS DEDGEMVKKA RRNSRMAPIG NMVTWDVKDA LELEAPDDKG
ILICNPPYGE RMGEEVEELY TRLGDLFKQK FLGYDCWVVS SNTDALKHIG LRPSRKIKVF
NGNLECSLRQ FQVFAGSKKY DNSEDEADGV IPKPRGVRRE NRKKIEKPVE ETTLQSEKES
ENEVEKKEYN PTRRVIETPA SEKPRKSAAS RYGSAKSAYL PVEDNKEEET EDAVKPHEDK
VEEETPKKTV KQERKPRLGA SKYGQTPKFL KRTQSDEETI EESSKEVEEI QSESISDKVE
RDAQDSSSDS SEEEMSLKDK IAEMKRKREE
//
