ID   A0A3E2H0J4_SCYLI        Unreviewed;       505 AA.
AC   A0A3E2H0J4;
DT   16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT   16-JAN-2019, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   RecName: Full=Phosphotransferase {ECO:0000256|RuleBase:RU362007};
DE            EC=2.7.1.- {ECO:0000256|RuleBase:RU362007};
DE   Flags: Fragment;
GN   ORFNames=B7463_g9818 {ECO:0000313|EMBL:RFU26513.1};
OS   Scytalidium lignicola (Hyphomycete).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Leotiomycetes incertae sedis; Scytalidium.
OX   NCBI_TaxID=5539 {ECO:0000313|EMBL:RFU26513.1, ECO:0000313|Proteomes:UP000258309};
RN   [1] {ECO:0000313|EMBL:RFU26513.1, ECO:0000313|Proteomes:UP000258309}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 105466 {ECO:0000313|EMBL:RFU26513.1,
RC   ECO:0000313|Proteomes:UP000258309};
RA   Buettner E., Gebauer A.M., Hofrichter M., Liers C., Kellner H.;
RT   "Draft genome sequence of Scytalidium lignicola DSM 105466, a ubiquitous
RT   saprotrophic fungus.";
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the hexokinase family.
CC       {ECO:0000256|ARBA:ARBA00009225, ECO:0000256|RuleBase:RU362007}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RFU26513.1}.
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DR   EMBL; NCSJ02000257; RFU26513.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3E2H0J4; -.
DR   STRING; 5539.A0A3E2H0J4; -.
DR   OMA; YHPNCRI; -.
DR   UniPathway; UPA00109; UER00180.
DR   Proteomes; UP000258309; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0005536; F:glucose binding; IEA:InterPro.
DR   GO; GO:0004396; F:hexokinase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0001678; P:intracellular glucose homeostasis; IEA:InterPro.
DR   CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR   Gene3D; 3.30.420.40; -; 1.
DR   Gene3D; 3.40.367.20; -; 2.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR001312; Hexokinase.
DR   InterPro; IPR022673; Hexokinase_C.
DR   InterPro; IPR022672; Hexokinase_N.
DR   PANTHER; PTHR19443:SF30; GLUCOKINASE-1-RELATED; 1.
DR   PANTHER; PTHR19443; HEXOKINASE; 1.
DR   Pfam; PF00349; Hexokinase_1; 1.
DR   Pfam; PF03727; Hexokinase_2; 2.
DR   PRINTS; PR00475; HEXOKINASE.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR   PROSITE; PS51748; HEXOKINASE_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU362007};
KW   Glycolysis {ECO:0000256|RuleBase:RU362007};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000256|RuleBase:RU362007};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU362007};
KW   Reference proteome {ECO:0000313|Proteomes:UP000258309};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU362007}.
FT   DOMAIN          2..178
FT                   /note="Hexokinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00349"
FT   DOMAIN          188..370
FT                   /note="Hexokinase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03727"
FT   DOMAIN          439..494
FT                   /note="Hexokinase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03727"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:RFU26513.1"
FT   NON_TER         505
FT                   /evidence="ECO:0000313|EMBL:RFU26513.1"
SQ   SEQUENCE   505 AA;  54861 MW;  69941EC536272DBA CRC64;
     MSQIPSYVTA VPDGTETGLY LAVDLGGTNL RVCSVDLHGD TTFTINQCKV AVPPRLMTAD
     TAAELFAFLA EQLDLFLQQH HEDMLRTYRA KKAAISATGH GFDYKDSLFL GFTFSFTFEQ
     EALDRGTMLR WTKGFNIPDA MGRDICEMFQ TEIDRLNLPV KVVALVNDTV GTLLARSYTS
     PGNSKTLLGA IFGTGTNGAY VEKTQDITKL DPVHQERSQE MILNTEWGSF DNELLVLPNT
     SYDEEVDRES VHPGIQLFEK RTSGMYLGEV LRHVLLAMAS VTPSIAATGL SRLNNKSAID
     ASFLSMAASD NSDSLTILRK HLKDSLDIDS GKDVAEAVKI LALAIGRRAA RLAGVAVAGV
     VVKSGRLSTR AVSESAKGHS NIVVLESDLE SGINSGNSGK ILNPITLLYR YFISILGSWT
     SWLFGSSTYQ SRIEELGIID VGVSGSLIEF YPGFEEIARS TLRDIEEIGS AGERRIRIGI
     ARDGSGVGAA LAARMAEQAR GRDIR
//