ID   A0A3E2HNB6_SCYLI        Unreviewed;       482 AA.
AC   A0A3E2HNB6;
DT   16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT   16-JAN-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Steroid 5-alpha reductase C-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
DE   Flags: Fragment;
GN   ORFNames=B7463_g1509 {ECO:0000313|EMBL:RFU34803.1};
OS   Scytalidium lignicola (Hyphomycete).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Leotiomycetes incertae sedis; Scytalidium.
OX   NCBI_TaxID=5539 {ECO:0000313|EMBL:RFU34803.1, ECO:0000313|Proteomes:UP000258309};
RN   [1] {ECO:0000313|EMBL:RFU34803.1, ECO:0000313|Proteomes:UP000258309}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 105466 {ECO:0000313|EMBL:RFU34803.1,
RC   ECO:0000313|Proteomes:UP000258309};
RA   Buettner E., Gebauer A.M., Hofrichter M., Liers C., Kellner H.;
RT   "Draft genome sequence of Scytalidium lignicola DSM 105466, a ubiquitous
RT   saprotrophic fungus.";
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RFU34803.1}.
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DR   EMBL; NCSJ02000016; RFU34803.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3E2HNB6; -.
DR   Proteomes; UP000258309; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.120.1630; -; 1.
DR   InterPro; IPR010721; UstE-like.
DR   PANTHER; PTHR32251; 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE; 1.
DR   PANTHER; PTHR32251:SF35; DUF1295 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_2G02670); 1.
DR   Pfam; PF06966; DUF1295; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000258309};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        53..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        149..174
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        194..210
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          444..464
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        449..464
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:RFU34803.1"
FT   NON_TER         482
FT                   /evidence="ECO:0000313|EMBL:RFU34803.1"
SQ   SEQUENCE   482 AA;  55306 MW;  20D26D8CB43D2B06 CRC64;
     MALPMITALT DCSNFSITVL PYIPQLYDLP PKLLQSQSNA AELYDIYLNT NPLVTAVAFS
     LFLAPIFLVV SEINRNYSQV DRCWGILPTI YNAHYAAYAH LTGLPTQRLD TLVAFSALRL
     TFNYWRKGGY SIGSEDYRWK IVQSKISPAL FFILNVVFIS FFQSVLLCLL AAPTYIILLA
     SRFQESMSMS TPDILFFSTL MGLVLVEYFA DQQQWNFQTA KAAYHKTAKR NKFDPEDLDR
     GFLVSGLWSW SRHPNFAAEQ TIWLVLYQWT CSVTAQKYPD YKEYQKRVGK FVPNLIRGLP
     GDFSDQKFKP TVEQKTRRVA TPNFFQHGSK YNWINIKMEA EKYSSESEDS PPAANPDKVQ
     NRLAVRFDEQ AIVNSKSTTT KTQRILPINL APLRPSLTRY VTSSGHPLEP MSRDYPKPTA
     EPHIAELLTR PPLKGTFSYN LQSSKNHYLE GDTAKETRDP DGLERAKKHW LRIAEELKKQ
     RR
//