ID A0A3E2J4V5_9BACI Unreviewed; 598 AA.
AC A0A3E2J4V5;
DT 16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT 16-JAN-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=D0463_15720 {ECO:0000313|EMBL:RFU61003.1};
OS Bacillus sp. V59.32b.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=1758642 {ECO:0000313|EMBL:RFU61003.1, ECO:0000313|Proteomes:UP000258625};
RN [1] {ECO:0000313|EMBL:RFU61003.1, ECO:0000313|Proteomes:UP000258625}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=V59.32a {ECO:0000313|EMBL:RFU61003.1,
RC ECO:0000313|Proteomes:UP000258625};
RA Seuylemezian A., Vaishampayan P.;
RT "Bacillus chawlae sp. nov., Bacillus glennii sp. nov., and Bacillus saganii
RT sp. nov. Isolated from the Vehicle Assembly Building at Kennedy Space
RT Center where the Viking Spacecraft were Assembled.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RFU61003.1}.
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DR EMBL; QVTC01000073; RFU61003.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3E2J4V5; -.
DR Proteomes; UP000258625; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF06580; His_kinase; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:RFU61003.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000258625};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 31..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 296..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 320..372
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
SQ SEQUENCE 598 AA; 68627 MW; 4DDC0929DEBF64BA CRC64;
MWKFRYKGLQ AMKDVLRTMI KFLDSSIKRK MIVMVVVTLI FVVGMIDIVT YGVSINLQMN
DAKANDARKV QFVIENIDET ISNMSSLMDS ISQDAEIQSM LSNSSVISVS NLEKIIFSKT
SYSSNIFEHL YLYDNQKLII KLNFNSGNKT NRNMINQTTF NKYRFDTVGR TSWRIENGVI
YIDKAIRQRE SLKILGYITI ALKEDYMKQR LQSEEYRYTY VFNENGDVIV SSNKIAELNL
DELYSRAKQE PNGIPTQLNI KPFGKMIFTT NISEFGKWRV VSLVPVKEIA KGPELIGWWI
MIIGFLGILV GIIITWKGTK RLIAPLYQLK QVMDQVETGY FKQNVNIQSN DEFARLGRSF
NRMMEEINHL ISEVYQKELS QRESEYKALK AQINPHFLYN TLDTIRWLAL YGESKKIEKV
AISLAHLLKA SLKESKEMIP IKTEMEYINA YLFIQQTRFE KINVSIYLDE DITNFFIPRF
ILQPLVENSF IHGLEKKVGN GNLIISGSVS HQSLTIRVID NGVGMNQEEA QLLLSAKEDE
HIDIAKGTGK GLKNVNKRIQ ALFGEEYGLS IQSSLDTGTI VEIMLPAIKH SIMTSKSI
//
