ID   A0A3E2N763_9CLOT        Unreviewed;       437 AA.
AC   A0A3E2N763;
DT   16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT   16-JAN-2019, sequence version 1.
DT   24-JAN-2024, entry version 12.
DE   SubName: Full=GHKL domain-containing protein {ECO:0000313|EMBL:RFZ76838.1};
GN   ORFNames=DS742_21470 {ECO:0000313|EMBL:RFZ76838.1};
OS   Clostridium indicum.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=759821 {ECO:0000313|EMBL:RFZ76838.1, ECO:0000313|Proteomes:UP000260680};
RN   [1] {ECO:0000313|EMBL:RFZ76838.1, ECO:0000313|Proteomes:UP000260680}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PI-S10-A1B {ECO:0000313|EMBL:RFZ76838.1,
RC   ECO:0000313|Proteomes:UP000260680};
RA   Krishna G., Summeta K., Shikha S., Prabhu P.B., Suresh K.;
RT   "New species, Clostridium PI-S10-A1B.";
RL   Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RFZ76838.1}.
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DR   EMBL; QOHO01000072; RFZ76838.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3E2N763; -.
DR   OrthoDB; 1656061at2; -.
DR   Proteomes; UP000260680; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR032834; NatK_C.
DR   PANTHER; PTHR40448; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR   PANTHER; PTHR40448:SF1; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR   Pfam; PF14501; HATPase_c_5; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000260680};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        26..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        51..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        76..96
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        116..136
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        156..173
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        179..206
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          329..432
FT                   /note="Sensor histidine kinase NatK C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14501"
SQ   SEQUENCE   437 AA;  50557 MW;  4CC489539BF8FC25 CRC64;
     MTYFIYTFTG GLCNYFSCVN LLPKKLSVLK SFLLFLYAFG SLFLFNHVYG QAGTFITLTG
     ILIIVCIITK NDYLSLGCYL FGYLYIIAFN YLFMYIAGEV LKMDMISMLK HDIMNIAFSC
     LYCVYCGVTT KLIGIFIHKK LNISKYLTNQ HMLKAILIDL FLLVFFFVFN FSYGERLGYN
     YGVIALNGII FLLLFSITVF LMYSIYKVTM GEQAYKFRMA QYENLQSYTE KLENSYGIMR
     KFKHDYMNIL STMSGFMEEN DMDGLIEYYE KRVLPISHSF SESDTKLGAL SKIKDTAMKS
     LLSSKFIYTM EIGINLKIEL TEIIDDLVMD TLDLSRIIGI FLDNSIEAAM DTNEKELYYC
     MFYRDNDLYI IIRNTSLPLS HAISQLCSHG ISTKGEDRGV GLYNVSLILS NYNNIIWDTT
     YEEPYFTQKL ILRKGVK
//