ID   A0A3E2XMU3_9FIRM        Unreviewed;       107 AA.
AC   A0A3E2XMU3;
DT   16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT   16-JAN-2019, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Sodium:proton antiporter {ECO:0000313|EMBL:RGC48777.1};
GN   ORFNames=DW070_07050 {ECO:0000313|EMBL:RGB80293.1}, DW747_05775
GN   {ECO:0000313|EMBL:RGC48777.1};
OS   Coprococcus catus.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Coprococcus.
OX   NCBI_TaxID=116085 {ECO:0000313|EMBL:RGC48777.1, ECO:0000313|Proteomes:UP000261231};
RN   [1] {ECO:0000313|Proteomes:UP000260773, ECO:0000313|Proteomes:UP000261231}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF45-17 {ECO:0000313|EMBL:RGB80293.1,
RC   ECO:0000313|Proteomes:UP000260773}, and AM28-39
RC   {ECO:0000313|EMBL:RGC48777.1, ECO:0000313|Proteomes:UP000261231};
RA   Zou Y., Xue W., Luo G.;
RT   "A genome reference for cultivated species of the human gut microbiota.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F
CC       family. {ECO:0000256|ARBA:ARBA00009212}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RGC48777.1}.
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DR   EMBL; QVEP01000012; RGB80293.1; -; Genomic_DNA.
DR   EMBL; QVFD01000004; RGC48777.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3E2XMU3; -.
DR   OrthoDB; 9799958at2; -.
DR   Proteomes; UP000260773; Unassembled WGS sequence.
DR   Proteomes; UP000261231; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015075; F:monoatomic ion transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR007208; MrpF/PhaF-like.
DR   PANTHER; PTHR34702:SF1; ANTIPORTER SUBUNIT MNHF2-RELATED; 1.
DR   PANTHER; PTHR34702; NA(+)/H(+) ANTIPORTER SUBUNIT F1; 1.
DR   Pfam; PF04066; MrpF_PhaF; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261231};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        6..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        37..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        63..86
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   107 AA;  12048 MW;  982E02A09A1D31E9 CRC64;
     MDAAFKSFFL VCIIVLAVLT FFCLVRTIKG PRLVDRIVGT NMIGTMTIAI IALLAAYLNE
     SSILDICLIY AIMSFVAVIV LTKIYIGIYN EKKSRQSRIE EESQDEY
//