ID A0A3F2V5A9_9GAMM Unreviewed; 596 AA.
AC A0A3F2V5A9;
DT 16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT 16-JAN-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=D6160_09075 {ECO:0000313|EMBL:RLP54950.1};
OS Ketobacter sp.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Ketobacteraceae; Ketobacter.
OX NCBI_TaxID=2083498 {ECO:0000313|EMBL:RLP54950.1, ECO:0000313|Proteomes:UP000280615};
RN [1] {ECO:0000313|EMBL:RLP54950.1, ECO:0000313|Proteomes:UP000280615}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BinD {ECO:0000313|EMBL:RLP54950.1};
RA Xu J.;
RT "Metagenomic reconstruction reveals the metabolic diversity of the novel
RT genus Ketobacter and the trajectory of genomic evolution within the
RT Alcanivoraceae family.";
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RLP54950.1}.
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DR EMBL; RAHY01000005; RLP54950.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3F2V5A9; -.
DR Proteomes; UP000280615; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR CDD; cd18773; PDC1_HK_sensor; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR PANTHER; PTHR45528; SENSOR HISTIDINE KINASE CPXA; 1.
DR PANTHER; PTHR45528:SF9; SENSOR HISTIDINE KINASE YRKQ; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08447; PAS_3; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:RLP54950.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000280615};
KW Transferase {ECO:0000313|EMBL:RLP54950.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 319..337
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 339..391
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 396..469
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT COILED 372..399
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 596 AA; 66464 MW; A12B5B68257C46B1 CRC64;
MDRREPRRWF APTIQNKLLA VMLVVALTPL MVFGALAYFK SRETVINQVG ERLQAASLLA
MSQIDRTFGF SLENIRSWAD LDTLQAVERG DPEGSISHML GDYQKAYGVY NTLVAVDEDA
SVVAAGDPAL LGVSVTSADW YKRVMASGKP YMAPLRYDSD LGGYGVSLAV PIFKKYSDGY
IIGVLKASLD WRELLQQVTA IEVVPEGQVP DGYAVLIDSE GYILAAPDFI LFSMESTLPE
AGMARVYDSR WWVAENPMLL DRVLKRPGHR YIRRGNDELM LVNMPASEFR YIGKTGWSLV
LVRNAKSALQ DIEYIRERAF LIGIITVLLI GLVAYIMSRQ IGSPITRLSR WAEQLSHGSL
DSNISLRSND ELAQLASALD NMRRNLKKYL DELFDSKERY QSIISSIDCV VWEAHINPLK
VTLLSGQVDH VLGRSPDQVL SHLDSWQSLV HSDHHSLLID ACTTAIERGT DTYVEFKFLH
GNGNWMWVKA LISVTIEDLG VVGLRGVVVD INDIVIAAEE MAEARDIALK TAEDKSRFMA
IVSHEIRTPI NGMLGMLDML SGQAGVDEQQ QTLSMAKRSG RNLLALVDEV MDFSRL
//
