ID   A0A3F2YWI5_9DIPT        Unreviewed;       560 AA.
AC   A0A3F2YWI5;
DT   16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT   16-JAN-2019, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=Methyltransferase domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Anopheles epiroticus.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=199890 {ECO:0000313|EnsemblMetazoa:AEPI015428-PA, ECO:0000313|Proteomes:UP000075885};
RN   [1] {ECO:0000313|Proteomes:UP000075885}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Epiroticus2 {ECO:0000313|Proteomes:UP000075885};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Howell P., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles epiroticus epiroticus2.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AEPI015428-PA}
RP   IDENTIFICATION.
RC   STRAIN=Epiroticus2 {ECO:0000313|EnsemblMetazoa:AEPI015428-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
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DR   AlphaFoldDB; A0A3F2YWI5; -.
DR   STRING; 199890.A0A3F2YWI5; -.
DR   EnsemblMetazoa; AEPI015428-RA; AEPI015428-PA; AEPI015428.
DR   VEuPathDB; VectorBase:AEPI015428; -.
DR   Proteomes; UP000075885; Unassembled WGS sequence.
DR   GO; GO:0016274; F:protein-arginine N-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 2.70.160.11; Hnrnp arginine n-methyltransferase1; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR049482; ANM3-like_C2H2_Zf.
DR   InterPro; IPR025799; Arg_MeTrfase.
DR   InterPro; IPR025714; Methyltranfer_dom.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   PANTHER; PTHR11006; PROTEIN ARGININE N-METHYLTRANSFERASE; 1.
DR   PANTHER; PTHR11006:SF114; PROTEIN ARGININE N-METHYLTRANSFERASE 3; 1.
DR   Pfam; PF21137; ANM3_C2H2_Zf; 1.
DR   Pfam; PF13847; Methyltransf_31; 1.
DR   SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   PROSITE; PS51678; SAM_MT_PRMT; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW   ProRule:PRU01015};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW   ECO:0000256|PROSITE-ProRule:PRU01015};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW   ProRule:PRU01015}.
FT   DOMAIN          67..112
FT                   /note="Protein arginine N-methyltransferase 3-like C2H2
FT                   zinc finger"
FT                   /evidence="ECO:0000259|Pfam:PF21137"
FT   DOMAIN          287..395
FT                   /note="Methyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF13847"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          206..226
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          165..199
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   560 AA;  63872 MW;  42180649C276A6BE CRC64;
     MSDGEDCPPL CDMDAVDDSN GEDDEWEVAE EQNDPVKCLF CEAISPTMTV AIRHAKQQHD
     FDLAGVRRRF HLDEYSYIKM INYIRREKPA PEHFKTASGS SLPWADDKYL QPVENETWLM
     FDLDELDEIM LNNGGGGGVG VNGVSGAIEN GNELGDTMTL TTDQYRKLQG IINDLTAQLR
     EKENLLQHAA SSIEKMKESF RHVVAEQQQP NGKDSGKGDA EEGAEGDKKL EQIKRKLEHC
     VSSVSVDDDQ SYFNTYSHFG IHHDMLSDEV RTSSYRDAIL RNADIMKDKT VLDLGCGTAI
     LSMFASKAGA KEVISVDQSD IIYQAMDIVR RNNIDNIRFV KGRLEDTELP VEKVDIIVSE
     WMGYFLLFEG MMDSVIHARK QYLREGGLIL PNRCNISIAG YGDLERHNEF IGFWKNVYGF
     DMSCMKREVL REATVEVCKP EHIITNANII ANFDLMEVDV DCPNFSYDFE LLVKRDTQLT
     AIIGYFDTFF ELPEHIEFST SPYSRPTHWK QTIFYLEEPV PVREGQKVCG KFICRRDPKD
     VRSLFINIEV LNMVLKYTLN
//