ID   A0A3F3Q2L3_9EURO        Unreviewed;      1275 AA.
AC   A0A3F3Q2L3;
DT   16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT   16-JAN-2019, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   RecName: Full=NACHT domain-containing protein {ECO:0000259|Pfam:PF05729};
GN   ORFNames=BDQ94DRAFT_178940 {ECO:0000313|EMBL:RDH32916.1};
OS   Aspergillus welwitschiae.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=1341132 {ECO:0000313|EMBL:RDH32916.1, ECO:0000313|Proteomes:UP000253729};
RN   [1] {ECO:0000313|EMBL:RDH32916.1, ECO:0000313|Proteomes:UP000253729}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 139.54b {ECO:0000313|EMBL:RDH32916.1,
RC   ECO:0000313|Proteomes:UP000253729};
RG   DOE Joint Genome Institute;
RA   Vesth T.C., Nybo J., Theobald S., Brandl J., Frisvad J.C., Nielsen K.F.,
RA   Lyhne E.K., Kogle M.E., Kuo A., Riley R., Clum A., Nolan M., Lipzen A.,
RA   Salamov A., Henrissat B., Wiebenga A., De vries R.P., Grigoriev I.V.,
RA   Mortensen U.H., Andersen M.R., Baker S.E.;
RT   "The genomes of Aspergillus section Nigri reveals drivers in fungal
RT   speciation.";
RL   Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KZ852048; RDH32916.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3F3Q2L3; -.
DR   STRING; 1341132.A0A3F3Q2L3; -.
DR   OrthoDB; 2477625at2759; -.
DR   Proteomes; UP000253729; Unassembled WGS sequence.
DR   Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR10039; AMELOGENIN; 1.
DR   PANTHER; PTHR10039:SF14; NACHT AND TPR DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_7G06670); 1.
DR   Pfam; PF12796; Ank_2; 1.
DR   Pfam; PF05729; NACHT; 1.
DR   SMART; SM00248; ANK; 5.
DR   SUPFAM; SSF48403; Ankyrin repeat; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 1.
PE   4: Predicted;
KW   ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW   Reference proteome {ECO:0000313|Proteomes:UP000253729}.
FT   DOMAIN          406..574
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|Pfam:PF05729"
FT   REPEAT          887..919
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REGION          1..112
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1171..1226
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        88..112
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1202..1218
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1275 AA;  143523 MW;  DC450E99B58E47AB CRC64;
     MGGLREKALR RLHRFRHKEP AVDNQSTAPD GSRSETVEPA KESPRRRSAS LVSSKGSICN
     WDPHQEDELR SLTGTRRPLS TIDARGEASS VKSEEKVSDS STPESSKELY DDGKKHRNLW
     KEAYERLPPT RRDRLRKLGY EPGSKTSEEG VLYILLNDLQ KKRVLCEKKA WKYKNKFLVR
     DYAAKCATWV KLIGDLVVPF APSQAAGPWG LIKVALEIPV KFADEMTALL GTVERVLQAT
     YRGREYESAY ATRNSAIADT LSQDLVSVYQ VVLELLSYSI DMLSKSTWAR VLDTMFDESS
     GLFSDLTAKE EELAKTAQAC SAATDKKILK HLQDIGGHLP RIEAQVADQL KKLDWEEAMR
     ILDWISSVKY GSHHDTVSGN RTPGTGEWLL QHHTFRDWEE SSSSAVLWLR GSPGVGKTYL
     TSKVIDHVQH TLTRCPNDEG FAYFYCNRTE DIRTRPLAVA QSYVRQLSSS LSKRSSSYIQ
     SRFKSTYEEL SMRGSDLDFE RCRILLTDSL NLYPRTTLVL DAFDECDRAS RGNLIQLFED
     LLSSSRRPVK LFIASRPDGD VQQQVRSHPN IEVLATDNHQ DIQTYISQEM VKMNRMNSAF
     GKLQEEIEST LLEKCQGMFQ WTYLQLKQLG ACTTPEAIRE CLGALPESLD ETYDGLYEEI
     ENNPPHDRDL ALRALKWVLA AREPLSREDL LEAVRINPDL MTTELCTPIS EDNLLSLCRY
     FLVIDSERDV WRVSHLSVAE YFELRRGWNA VVTNLMVGKA CLLFMLSDTC WNEIMCQWAA
     RPWLYEPGKS DFLRPLLYYV TCYWPEHIAI LEHAGASKDD LSSVTELLER FLGDPQDSSA
     QYQTWARWRT FEPAKYSILA VCEYGFHQVL DRWWNMAQLN HTFTNIRGET YMMIAARKGH
     VPILRILLKK GGAVGEQGDK GRSSTPLIAA VNGRNFEAAN FLLKEGNADV NLEVDDMFPH
     MSCALEVAVN NRHLDMVQFL ASEGCTHTNT HLRYSTCGSL LVVATLKGWF QGIKTLVEQG
     GADVNLVLQY GKYGSALECA LTHLYDCQAI VEYLVHTQKA DVNLAVQTGE YGSALAAAVE
     RGELQYVLFL IDIGKADVNM PLPNFPYGSA LARAAFLAGE AFRKPLYHGR ISGLTEIVRI
     LLEEGALVVL DIGKGEIVDA IEACNGRPRL SPKWMLTNDE DPNENNGGKD DTTSDADNAN
     DEIDANTADD EEGTLDAPGV LDGDDADNER VRKAKLLVKA MLADLHKEMW QQYKSGALGI
     EEAKYVDAKY GQTKP
//