ID A0A3F3Q6T0_9EURO Unreviewed; 678 AA.
AC A0A3F3Q6T0;
DT 16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT 16-JAN-2019, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=protein-tyrosine-phosphatase {ECO:0000256|ARBA:ARBA00013064};
DE EC=3.1.3.48 {ECO:0000256|ARBA:ARBA00013064};
GN ORFNames=BDQ94DRAFT_16350 {ECO:0000313|EMBL:RDH34881.1};
OS Aspergillus welwitschiae.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=1341132 {ECO:0000313|EMBL:RDH34881.1, ECO:0000313|Proteomes:UP000253729};
RN [1] {ECO:0000313|EMBL:RDH34881.1, ECO:0000313|Proteomes:UP000253729}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 139.54b {ECO:0000313|EMBL:RDH34881.1,
RC ECO:0000313|Proteomes:UP000253729};
RG DOE Joint Genome Institute;
RA Vesth T.C., Nybo J., Theobald S., Brandl J., Frisvad J.C., Nielsen K.F.,
RA Lyhne E.K., Kogle M.E., Kuo A., Riley R., Clum A., Nolan M., Lipzen A.,
RA Salamov A., Henrissat B., Wiebenga A., De vries R.P., Grigoriev I.V.,
RA Mortensen U.H., Andersen M.R., Baker S.E.;
RT "The genomes of Aspergillus section Nigri reveals drivers in fungal
RT speciation.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KZ852042; RDH34881.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3F3Q6T0; -.
DR STRING; 1341132.A0A3F3Q6T0; -.
DR OrthoDB; 2045814at2759; -.
DR Proteomes; UP000253729; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:GOC.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR GO; GO:0033260; P:nuclear DNA replication; IEA:InterPro.
DR CDD; cd14516; DSP_fungal_PPS1; 1.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 2.
DR InterPro; IPR000340; Dual-sp_phosphatase_cat-dom.
DR InterPro; IPR047949; PPS1_DSP.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR016130; Tyr_Pase_AS.
DR InterPro; IPR003595; Tyr_Pase_cat.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR InterPro; IPR020422; TYR_PHOSPHATASE_DUAL_dom.
DR PANTHER; PTHR47550; DUAL SPECIFICITY PROTEIN PHOSPHATASE PPS1; 1.
DR PANTHER; PTHR47550:SF1; DUAL SPECIFICITY PROTEIN PHOSPHATASE PPS1; 1.
DR Pfam; PF00782; DSPc; 1.
DR SMART; SM00195; DSPc; 1.
DR SMART; SM00404; PTPc_motif; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 2.
DR PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR PROSITE; PS50054; TYR_PHOSPHATASE_DUAL; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protein phosphatase {ECO:0000256|ARBA:ARBA00022912};
KW Reference proteome {ECO:0000313|Proteomes:UP000253729}.
FT DOMAIN 501..649
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50054"
FT DOMAIN 568..636
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
FT REGION 1..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..37
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..53
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 56..73
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 678 AA; 75667 MW; 45621517D9D0F0FF CRC64;
MATVVVQQQT LRHSTPPPTG LTPALSLNRT SSPIPNKHIP VCPTGPSPIN AHAPSPPVKD
SSNDQTSSLL YPPDKSRRLT HSPTVYTIDL KTLSASLEHL AAQPLPHPNL VFPWLHGLHP
DNHLQVGFFT KGKRSLRRTP KCWRGITIVK VGGDLSSCRI KGAVSPEEVL APSGVEFLAI
DPREGLSVRN FQIQTAKLAP LSDIIVYGEN SATQQQILDI ARRMATAQHN WRIKNDPDRN
SPAYNTFVLD CAFSEVEKKA SHLVAISSSG QLTGQVVDFF QWERLEMCEM SKASEISTNV
WLGPTPDYLL RPGSCGPAPT ENFDLLIEAS ELASIPGPRF LANLNKQLEE GPQKLEFPSS
GSILLPSGET REIDDLVNTV RWIYYLANPD EPDQKADADG DIPMIPLTKT ARKILIHCPD
GYTESSLLAI AYLMFAEGIS APNAWLRLHC EKKRNFFAYP SDITFMSGVQ RRLLQESPAT
RSHKIRSLPD PAWFRYCDGS LPSRILPYMY LGNLSHANNP EMLSALGIKR ILSIGETVSW
SSTSAKVDEK DILHITNVQD NGIDELTKEF DRCLDFIRQG KHDGMATLVH CRVGVSRSAT
ICIAEVMASL GLSFPRAYCF VRARRLNVII QPHLRFVYEL LKWEELQLQK RNKPARRELE
WATVAREIAL MNKPYSRQ
//
