ID A0A3F3QDK5_9EURO Unreviewed; 275 AA.
AC A0A3F3QDK5;
DT 16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT 16-JAN-2019, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE RecName: Full=Hsp70 nucleotide exchange factor FES1 {ECO:0000256|ARBA:ARBA00020719};
DE AltName: Full=Hsp70 nucleotide exchange factor fes1 {ECO:0000256|ARBA:ARBA00015214};
GN ORFNames=BDQ94DRAFT_156959 {ECO:0000313|EMBL:RDH37328.1};
OS Aspergillus welwitschiae.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=1341132 {ECO:0000313|EMBL:RDH37328.1, ECO:0000313|Proteomes:UP000253729};
RN [1] {ECO:0000313|EMBL:RDH37328.1, ECO:0000313|Proteomes:UP000253729}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 139.54b {ECO:0000313|EMBL:RDH37328.1,
RC ECO:0000313|Proteomes:UP000253729};
RG DOE Joint Genome Institute;
RA Vesth T.C., Nybo J., Theobald S., Brandl J., Frisvad J.C., Nielsen K.F.,
RA Lyhne E.K., Kogle M.E., Kuo A., Riley R., Clum A., Nolan M., Lipzen A.,
RA Salamov A., Henrissat B., Wiebenga A., De vries R.P., Grigoriev I.V.,
RA Mortensen U.H., Andersen M.R., Baker S.E.;
RT "The genomes of Aspergillus section Nigri reveals drivers in fungal
RT speciation.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Functions as a nucleotide exchange factor (NEF) for Hsp70
CC chaperones which accelerates the release of ADP. Required for fully
CC efficient Hsp70-mediated folding of proteins.
CC {ECO:0000256|ARBA:ARBA00024912}.
CC -!- SIMILARITY: Belongs to the FES1 family.
CC {ECO:0000256|ARBA:ARBA00011045}.
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DR EMBL; KZ852035; RDH37328.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3F3QDK5; -.
DR STRING; 1341132.A0A3F3QDK5; -.
DR OrthoDB; 5473057at2759; -.
DR Proteomes; UP000253729; Unassembled WGS sequence.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR013918; Nucleotide_exch_fac_Fes1.
DR PANTHER; PTHR19316:SF18; HSP70-BINDING PROTEIN 1; 1.
DR PANTHER; PTHR19316; PROTEIN FOLDING REGULATOR; 1.
DR Pfam; PF08609; Fes1; 1.
DR Pfam; PF13513; HEAT_EZ; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000253729}.
FT DOMAIN 5..98
FT /note="Nucleotide exchange factor Fes1"
FT /evidence="ECO:0000259|Pfam:PF08609"
FT REGION 16..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 275 AA; 29984 MW; F04D573F591771E2 CRC64;
MDPNMNSLLK WSIKAATEEQ SSGENNNNNN SGNNAPADPS RGLTPQMLST LFGGPSEADL
MKAAMEALRS DEVDLENKLI AFDNFEQLIE SIDNANNLEP LGLWTPLVEL LDHKEPDMRR
MAAWCIGTAV QNNEKAQDKL IVLNALPKLV SLATADTTPV VRKKAVYAIS SAVRNYQPAM
DEVTKSLPEG YSRDKIDAGD MDAPTFVTCT VDRMLSPSKP TSSSSGEHVV PLRGTRALRV
DRARALTMLA SGRHAVTGTR LSYEAQAIRP HLIPK
//
