ID A0A3G2G7M0_9FLAO Unreviewed; 526 AA.
AC A0A3G2G7M0;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Replicative DNA helicase {ECO:0000256|ARBA:ARBA00021957, ECO:0000256|RuleBase:RU362085};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551, ECO:0000256|RuleBase:RU362085};
GN Name=dnaB {ECO:0000313|EMBL:AYN00543.1};
GN ORFNames=EAG08_09650 {ECO:0000313|EMBL:AYN00543.1};
OS Chryseobacterium sp. 3008163.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Weeksellaceae;
OC Chryseobacterium group; Chryseobacterium.
OX NCBI_TaxID=2478663 {ECO:0000313|EMBL:AYN00543.1, ECO:0000313|Proteomes:UP000273471};
RN [1] {ECO:0000313|EMBL:AYN00543.1, ECO:0000313|Proteomes:UP000273471}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3008163 {ECO:0000313|EMBL:AYN00543.1};
RA Bekkelund A.K., Hansen B.R., Stokken H., Eriksen B.F., Kashulin N.A.;
RT "Effects of UV and annual dynamics of microbial communities in freshwater
RT RAS systems.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Participates in initiation and elongation during chromosome
CC replication; it exhibits DNA-dependent ATPase activity.
CC {ECO:0000256|RuleBase:RU362085}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665,
CC ECO:0000256|RuleBase:RU362085};
CC -!- SIMILARITY: Belongs to the helicase family. DnaB subfamily.
CC {ECO:0000256|ARBA:ARBA00008428, ECO:0000256|RuleBase:RU362085}.
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DR EMBL; CP033070; AYN00543.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3G2G7M0; -.
DR KEGG; chrs:EAG08_09650; -.
DR OrthoDB; 9773982at2; -.
DR Proteomes; UP000273471; Chromosome.
DR GO; GO:1990077; C:primosome complex; IEA:UniProtKB-UniRule.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003678; F:DNA helicase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006269; P:DNA replication, synthesis of RNA primer; IEA:UniProtKB-UniRule.
DR CDD; cd00984; DnaB_C; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036185; DNA_heli_DnaB-like_N_sf.
DR InterPro; IPR007692; DNA_helicase_DnaB.
DR InterPro; IPR007694; DNA_helicase_DnaB-like_C.
DR InterPro; IPR007693; DNA_helicase_DnaB-like_N.
DR InterPro; IPR016136; DNA_helicase_N/primase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR00665; DnaB; 1.
DR PANTHER; PTHR30153:SF2; REPLICATIVE DNA HELICASE; 1.
DR PANTHER; PTHR30153; REPLICATIVE DNA HELICASE DNAB; 1.
DR Pfam; PF00772; DnaB; 1.
DR Pfam; PF03796; DnaB_C; 1.
DR SUPFAM; SSF48024; N-terminal domain of DnaB helicase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51199; SF4_HELICASE; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU362085};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW ECO:0000256|RuleBase:RU362085};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU362085};
KW Helicase {ECO:0000256|RuleBase:RU362085, ECO:0000313|EMBL:AYN00543.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU362085};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU362085}; Primosome {ECO:0000256|RuleBase:RU362085};
KW Reference proteome {ECO:0000313|Proteomes:UP000273471}.
FT DOMAIN 195..473
FT /note="SF4 helicase"
FT /evidence="ECO:0000259|PROSITE:PS51199"
FT REGION 473..526
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 474..490
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 526 AA; 58241 MW; DCB07ECA03AD5127 CRC64;
MAQKETLSSL TQGNFARELS IADGKMPPNA VDFERLVVGT FLIDKKGLDH SIDLLTPEVF
YDPRHSVIFE VILKLYEGNQ PVDLMTVIQE LKKTDRLASA GGDHYIIELT MGVSSSAHIE
YHVRVILEKY ILRSLINVSA NVIDTSYKES TDVFELLDKA EQSFFEITNG TIKKGFDTAN
TLVKQAIDTI KSLKDKEGIS GVPSGFTGVD KETGGWQNSD LIIIAARPAM GKTAFLLSMA
RNIAVGHKIP MALFSLEMAS VQLITRMIAS ETKISSEKLR KGQMSDEEWQ RLFSNVSELE
NAPLYIDETP SLSIFDFRAK CRRLVMQHGV RIIMVDYLQL MTASSGGKGG GNREQEIAMI
SRSLKAIAKE LNVPVIALSQ LSRTVETRPG KRPQLSDLRE SGAIEQDADI VSFIFRPEYY
KIAVWDNDEE GQESSTENQA ELIIAKHRNG ATADVRLSFM KHFAKFGDIG ETDSSYPSGG
SQSHEPSGFE KIKTTIQPGA AFDLPDNSKV SGSSMNDLDD EDDFPF
//
