ID A0A3G2GBW8_9FLAO Unreviewed; 942 AA.
AC A0A3G2GBW8;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN Name=uvrA {ECO:0000313|EMBL:AYN02258.1};
GN ORFNames=EAG08_19875 {ECO:0000313|EMBL:AYN02258.1};
OS Chryseobacterium sp. 3008163.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Weeksellaceae;
OC Chryseobacterium group; Chryseobacterium.
OX NCBI_TaxID=2478663 {ECO:0000313|EMBL:AYN02258.1, ECO:0000313|Proteomes:UP000273471};
RN [1] {ECO:0000313|EMBL:AYN02258.1, ECO:0000313|Proteomes:UP000273471}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3008163 {ECO:0000313|EMBL:AYN02258.1};
RA Bekkelund A.K., Hansen B.R., Stokken H., Eriksen B.F., Kashulin N.A.;
RT "Effects of UV and annual dynamics of microbial communities in freshwater
RT RAS systems.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP033070; AYN02258.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3G2GBW8; -.
DR KEGG; chrs:EAG08_19875; -.
DR OrthoDB; 9809851at2; -.
DR Proteomes; UP000273471; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR CDD; cd03270; ABC_UvrA_I; 1.
DR CDD; cd03271; ABC_UvrA_II; 1.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 2.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004602; UvrA.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR InterPro; IPR041102; UvrA_inter.
DR NCBIfam; TIGR00630; uvra; 1.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF3; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR Pfam; PF17760; UvrA_inter; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000273471};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 607..939
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 942 AA; 105332 MW; 8EAB4ECBBD41CF75 CRC64;
MSESKEYIEV YGAREHNLKN IDVKIPRNEL VVITGLSGSG KSSLAFDTIF AEGQRRYIET
FSAYARQFLG GLERPDVDKI EGLSPVIAIE QKTTNKNPRS TVGTVTELYD YLRLLFARVS
DAYSQTTGKK LVSYTEDQIL DTIKENYKGE KLMLMAPVVR SRKGHYHELF VQMAKKGYGQ
ARIDGELQDI EYDLKLDRYK THDIDIVIDR WIIGESASET RMEKSLRTAM EMGEGVIGIQ
KLGSTDIEYF SKNLMDAETG HSLALPEPNT FSFNSPKGSC PSCKGLGTIK KINTDYFVEN
PKLSINQGGL LPLEDIKSNK WILAQIKNIL EIFGLGLTTP FKDIPAEALD YMYNGCHKEF
NKDLKYAGIA KKIKISFDGL IPFMEEIIDE KESYEGVLLE RHFTTEETCP ECKGARLQPG
SLSFKIDGKN IAEINGLSLS DLKDWLRDVK DKFSPKHAII AHEILKEIET RLQFLLDVGL
EYLSLSRSSK TLSGGESQRI RLATQIGSQL VNVLYILDEP SIGLHQRDNE RLIKSLKNLR
DIGNSVLVVE HDKDMIMEAD EVLDIGPRAG KFGGEILWQG KPEDLLKADT ITADYINGKR
KIAIPEVRRE GNGKSIVLKG ATGNNLKNVN LEIPLGKLVV VTGISGSGKS SLINGTLYPI
LNKHFYRAVQ EPLPYKKIEG LDNIDKIVDV DQTPIGRTPR SNPATYTGMF TDIRNLFSEL
PESKIRGYKP GRFSFNVKGG RCETCQGGGL KVIEMNFLPD VYVHCETCNG KRFNRETLEV
RYKGKSISDV LDMTIDEAVD FFQPIPKIFA RVKTLQDVGL GYITMGQQST TLSGGEAQRI
KLATELAKRQ TGNTLYILDE PTTGLHFEDV KILMDAINKL VELGNSFIII EHNMDVIKLA
DHIIDVGPEG GKYGGEIIAK GTPEEIIKSK KSLTGKYLKK EM
//
