ID A0A3G2JKM4_9ACTN Unreviewed; 381 AA.
AC A0A3G2JKM4;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=MerR family transcriptional regulator {ECO:0000313|EMBL:AYN42894.1};
GN ORFNames=D9753_32955 {ECO:0000313|EMBL:AYN42894.1};
OS Streptomyces dangxiongensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1442032 {ECO:0000313|EMBL:AYN42894.1, ECO:0000313|Proteomes:UP000268329};
RN [1] {ECO:0000313|EMBL:AYN42894.1, ECO:0000313|Proteomes:UP000268329}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Z022 {ECO:0000313|EMBL:AYN42894.1,
RC ECO:0000313|Proteomes:UP000268329};
RA Zhang B.;
RT "The genome of Streptomyces dangxiongensis Z022.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP033073; AYN42894.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3G2JKM4; -.
DR KEGG; sdd:D9753_32955; -.
DR OrthoDB; 9800334at2; -.
DR Proteomes; UP000268329; Chromosome.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd01104; HTH_MlrA-CarA; 1.
DR Gene3D; 1.10.1660.10; -; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 1.10.1240.10; Methionine synthase domain; 1.
DR InterPro; IPR003759; Cbl-bd_cap.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR000551; MerR-type_HTH_dom.
DR InterPro; IPR047057; MerR_fam.
DR InterPro; IPR036594; Meth_synthase_dom.
DR PANTHER; PTHR30204:SF96; MERR FAMILY REGULATORY PROTEIN; 1.
DR PANTHER; PTHR30204; REDOX-CYCLING DRUG-SENSING TRANSCRIPTIONAL ACTIVATOR SOXR; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF02607; B12-binding_2; 1.
DR Pfam; PF13411; MerR_1; 1.
DR SMART; SM00422; HTH_MERR; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF46955; Putative DNA-binding domain; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS50937; HTH_MERR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000268329}.
FT DOMAIN 22..91
FT /note="HTH merR-type"
FT /evidence="ECO:0000259|PROSITE:PS50937"
FT DOMAIN 242..370
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 81..157
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..124
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 381 AA; 38541 MW; FE9C0412122AEE25 CRC64;
MPGSGRVPES GRAGSAGAAE PGLTTGALAR RLGVSPTTLR SWDRRYGMGP AARVDGRHRR
WTPRDVTMLE TMCRLTASGV PPADAARAAK ERAYPAAPRP PADGAPTPAA APPAAAPPAL
AAPADPAAPA AGAPSPTVGA PSPTVGAPSP GAARQEGRGL ARAAVRLDAA AVGERLEAAV
DRYGVVAAWQ DVMLPTLHAV GRRWESSGDR YVEVEHLLSW QVSTTLRGHT RRPVATAGPT
GAGPVLLACV PGEQHTLPLE ALNAALSQLG IATRMFGAAV PADALVAAVR RLGPAAVVLW
AQARSTASLP LAEHVAAMEW GVKGARAQPL VMLGGPGWAG RPAPGMLRPA ALTEALAALV
IAYGAAEPVR PAAGAPPTSP H
//
